Results 91 to 100 of about 19,786,213 (303)

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

open access: yesAdvanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou   +3 more
wiley   +1 more source

Identification of attractive odorants released by preferred bacterial food found in the natural habitats of C. elegans. [PDF]

open access: yesPLoS ONE, 2018
Food choice is critical for survival because organisms must choose food that is edible and nutritious and avoid pathogenic food. Many organisms, including the nematode C. elegans, use olfaction to detect and distinguish among food sources. C.
Soleil E Worthy   +8 more
doaj   +1 more source

C. elegans and volatile anesthetics [PDF]

open access: yesWormBook, 2007
The mechanism of action of volatile anesthetics remains an enigma, despite their worldwide use. The nematode C. elegans has served as an excellent model to unravel this mystery. Genes and gene sets that control the behavior of the animal in volatile anesthetics have been identified, using multiple endpoints to mimic the phenomenon of anesthesia in man.
P G, Morgan, E-B, Kayser, M M, Sedensky
openaire   +2 more sources

Combinatorial Roles of Heparan Sulfate Proteoglycans and Heparan Sulfates in Caenorhabditis elegans Neural Development [PDF]

open access: yes, 2014
Heparan sulfate proteoglycans (HSPGs) play critical roles in the development and adult physiology of all metazoan organisms. Most of the known molecular interactions of HSPGs are attributed to the structurally highly complex heparan sulfate (HS) glycans.
Kinnunen, Tarja K.   +4 more
core   +1 more source

Interface‐Confined Cavitation at an MXene/TiO2 Schottky Heterointerface for Non‐Thermal Juice Preservation

open access: yesAdvanced Science, EarlyView.
This work establishes an MXene/TiO2 Schottky heterointerface for non‐thermal sonocatalysis. Interface‐confined cavitation and dynamic Ti3+/V₀ shuttles drive charge transport and reactive oxygen species (ROS) generation. The platform achieves 3‐log pathogen reduction while retaining heat‐labile nutrients in complex food matrices, redefining sonocatalyst
Xiaoge Wu   +5 more
wiley   +1 more source

The Microbial Zoo in the C. elegans Intestine: Bacteria, Fungi and Viruses

open access: yesViruses, 2018
C. elegans is an invaluable model organism that has been a driving force in many fundamental biological discoveries. However, it is only in the past two decades that it has been applied to host–pathogen interaction studies.
Hongbing Jiang, David Wang
doaj   +1 more source

Stable nuclear transformation of Eudorina elegans [PDF]

open access: yes, 2013
Lerche K, Hallmann A. Stable nuclear transformation of Eudorina elegans. BMC Biotechnology. 2013;13(1): 11.UNLABELLED: ABSTRACT: BACKGROUND: A fundamental step in evolution was the transition from unicellular to differentiated, multicellular organisms ...
Lerche, Kai   +5 more
core   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu   +5 more
wiley   +1 more source

Primer registro de un posible híbrido homoploide y de un tetraploide en el género Chaetanthera Ruiz & Pav. (Asteraceae) en Chile First report of a possible homoploid hybrid and a tetraploid in the genus Chaetanthera Ruiz & Pav. (Asteraceae) in Chile

open access: yesGayana: Botanica, 2012
En este trabajo se reportan cariotipos detallados de C. elegans Phil., C. x serrata Ruiz & Pav. y C. chilensis (Willd.) DC. Además, se registra por primera vez la presencia de un posible híbrido homoploide entre C. chilensis y C.
CARLOS BAEZA PERRY   +2 more
doaj  

Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art

open access: yesAdvanced Intelligent Discovery, EarlyView.
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser   +6 more
wiley   +1 more source

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