Results 81 to 90 of about 304,068 (299)

The Microbial Zoo in the C. elegans Intestine: Bacteria, Fungi and Viruses

Viruses, 2018
C. elegans is an invaluable model organism that has been a driving force in many fundamental biological discoveries. However, it is only in the past two decades that it has been applied to host–pathogen interaction studies.
Hongbing Jiang, David Wang
doaj   +1 more source

C. elegans noncoding RNA genes [PDF]

WormBook, 2005
The C. elegans genome contains approximately 1300 genes that produce functional noncoding RNA (ncRNA) transcripts. Here we describe what is currently known about these ncRNA genes, from the perspective of the annotation of the finished genome sequence. We have collated a reference set of C. elegans ncRNA gene annotation relative to the WS130 version of
Shawn L, Stricklin, Sam, Griffiths-Jones, Sean R, Eddy   +2 more
openaire   +2 more sources

Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor

Advanced Science, EarlyView.
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang, Yixiang Deng, Nan Xia, Shuzo Sugita, Shangbang Gao   +4 more
wiley   +1 more source

A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans. [PDF]

PLoS Genetics, 2011
The decline in immune function with aging, known as immunosenescence, has been implicated in evolutionarily diverse species, but the underlying molecular mechanisms are not understood.
Matthew J Youngman, Zoë N Rogers, Dennis H Kim   +2 more
doaj   +1 more source

Virulence behavior of uropathogenic Escherichia coli strains in the host model Caenorhabditis elegans [PDF]

, 2018
Urinary tract infections (UTIs) are among the most common bacterial infections in humans. Although a number of bacteria can cause UTIs, most cases are due to infection by uropathogenic Escherichia coli (UPEC).
Amos, Anastasi, Anyanful, Barber, Barnich, Beutin, Blango, Brennan, Brenner, Brzuszkiewicz, Burton, Caldwell, Chen, Chávez, Chávez, Clermont, Croxen, Dale, Dho-Moulin, Diard, Doonan, Edgar, Ewers, Ferrières, Foxman, Francisco, Fricke, Guyer, Hagberg, Hoeven, Hornef, Johnson, Johnson, Johnson, Johnson, Kampkötter, Kaper, Kim, King, Kӧhler, Longhi, Mahajan-Miklos, Manges, Martinez-Medina, Merkx-Jacques, Mi, Mobley, Mulvey, Mylonakis, Müller, Paiva, Pidgeon, Powell, Sifri, Soto, Stepanović, Tan, Thumbikat, Valdivia, Wirth, Zanni   +60 more
core   +1 more source

Wnt signaling in C. elegans [PDF]

WormBook, 2013
Wnt proteins are secreted lipid-modified glycoproteins that control many aspects of development in organisms ranging from sponges to vertebrates. Wnt proteins are also important regulators of C. elegans development, with functions in processes as diverse as cell fate specification, asymmetric cell division, cell migration and synapse formation. In this
Hitoshi, Sawa, Hendrik C, Korswagen
openaire   +2 more sources

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Identification of attractive odorants released by preferred bacterial food found in the natural habitats of C. elegans. [PDF]

PLoS ONE, 2018
Food choice is critical for survival because organisms must choose food that is edible and nutritious and avoid pathogenic food. Many organisms, including the nematode C. elegans, use olfaction to detect and distinguish among food sources. C.
Soleil E Worthy, Lillian Haynes, Melissa Chambers, Danika Bethune, Emily Kan, Kevin Chung, Ryan Ota, Charles J Taylor, Elizabeth E Glater   +8 more
doaj   +1 more source

Highly efficient optogenetic cell ablation in C. elegans using membrane-targeted miniSOG. [PDF]

, 2016
The genetically encoded photosensitizer miniSOG (mini Singlet Oxygen Generator) can be used to kill cells in C. elegans. miniSOG generates the reactive oxygen species (ROS) singlet oxygen after illumination with blue light.
Chisholm, Andrew D, Xu, Suhong
core   +1 more source