Results 81 to 90 of about 19,786,213 (303)
An evolutionarily conserved transcriptional response to viral infection in Caenorhabditis nematodes
BMC Genomics, 2017 Background Caenorhabditis elegans is a powerful model organism for probing many biological processes including host-pathogen interactions with bacteria and fungi. The recent identification of nematode viruses that naturally infect C.
Kevin Chen +4 more
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Characterization of aminopeptidase encoding gene anp-1 and its association with development in Caenorhabditis elegans [PDF]
PeerJ, 2019 Background Aminopeptidases play important roles in various biological processes in nematodes including growth, development and reproduction. Although the aminopeptidases have been shown to regulate reproduction in Caenorhabditis elegans (C. elegans), the
Shanchun Su +3 more
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Ascaroside signaling in C. elegans [PDF]
WormBook, 2013 Over the past 10 years, the relevance of small-molecule signaling for many aspects of C. elegans development and behavior has become apparent. One prominent group of small-molecule signals are the ascarosides, which control dauer entry and exit as well as a variety of sex-specific and social behaviors, including male attraction, hermaphrodite repulsion,
Andreas H, Ludewig, Frank C, Schroeder
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The functions of y-box binding proteins in caenorhabditis elegans [PDF]
, 2015 Members of the highly conserved family of Y-box binding proteins (YBPs) have a broad spectrum of functions in both transcriptional and post-transcriptional regulation of gene expression.
Arnold, Andreas
core +1 more source
Advanced Science, EarlyView.This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu +5 more
wiley +1 more source
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans. [PDF]
PLoS Genetics, 2011 The decline in immune function with aging, known as immunosenescence, has been implicated in evolutionarily diverse species, but the underlying molecular mechanisms are not understood.
Matthew J Youngman +2 more
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Wnt signaling in C. elegans [PDF]
WormBook, 2013 Wnt proteins are secreted lipid-modified glycoproteins that control many aspects of development in organisms ranging from sponges to vertebrates. Wnt proteins are also important regulators of C. elegans development, with functions in processes as diverse as cell fate specification, asymmetric cell division, cell migration and synapse formation. In this
Hitoshi, Sawa, Hendrik C, Korswagen
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Modern techniques for the analysis of chromatin and nuclear organization in C. elegans [PDF]
, 2016 Licensed under a Creative Commons Attribution License.In recent years, Caenorhabditis elegans has emerged as a new model to investigate the relationships between nuclear architecture, cellular differentiation, and organismal development.
Askjaer, Peter +2 more
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Advanced Science, EarlyView.Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu +12 more
wiley +1 more source