Results 1 to 10 of about 25,076 (227)

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

PLoS Pathogens, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Jessica C Jang, Gang Chen, Spencer H Wang, Mark A Barnes, Josiah I Chung, Mali Camberis, Graham Le Gros, Philip J Cooper, Cathy Steel, Thomas B Nutman, Mitchell A Lazar, Meera G Nair   +11 more
doaj   +23 more sources

Sensitive and accurate DNA metabarcoding of parasitic helminth mock communities using the mitochondrial rRNA genes

Scientific Reports, 2022
Next-generation sequencing technologies have accelerated the pace of helminth DNA metabarcoding research, enabling species detection in bulk community samples.
Abigail Hui En Chan, Naowarat Saralamba, Sompob Saralamba, Jiraporn Ruangsittichai, Kittipong Chaisiri, Yanin Limpanont, Vachirapong Charoennitiwat, Urusa Thaenkham   +7 more
doaj   +4 more sources

Widespread gene fusion artifacts in helminth genome annotations [PDF]

BMC Genomics
Background Current helminth genomes possess thousands of predicted fusion genes, encoding novel protein domain architectures that are unique to these species.
Emma L. Collington, Andrew C. Doxey, Brendan J. McConkey, D. Moira Glerum   +3 more
doaj   +2 more sources

Intestinal helminth Schyzocotyle acheilognathi Yamaguti, 1934 infection ameliorate lipid metabolism of grass carp (Ctenopharyngodon idella) through immune and gut microbiota regulation [PDF]

Frontiers in Microbiology
Fats have been widely applied in aquaculture to promote growth performance and substitute partial protein in fish feeds. However, excessive dietary fat levels induce metabolic disorders harming the health of cultured fish.
Xiaoao Yang, Denghui Zhu, Wenxiang Li, Peipei Fu   +3 more
doaj   +2 more sources

Delineating markers of disease-disease interaction: a systematic methodology and its application to multiple diabetes-helminth cohorts [PDF]

BMC Bioinformatics
Background Understanding how the molecules in our bodyrespond to the co-occurrence of two diseases in an individual (comorbidity) could lead tomechanistic insights into novel treatments for comorbid conditions.
Nilesh Subramanian, Philge Philip, Anuradha Rajamanickam, Nathella Pavan Kumar, Subash Babu, Manikandan Narayanan   +5 more
doaj   +2 more sources

Hookworm infection modulates lung and intestinal transcriptomic responses to SARS-CoV-2 in Syrian hamsters [PDF]

Frontiers in Immunology
BackgroundHelminth infections are widespread in resource-limited settings, and modulate host immune responses, with potential implications for viral coinfections.
Bruce A. Rosa, Mahdiyeh Bigham, Tamarand L. Darling, Ashutosh Arun, Kumar Sachin Singh, John Martin, Adrianus C. M. Boon, Adrianus C. M. Boon, Adrianus C. M. Boon, Makedonka Mitreva, Makedonka Mitreva, Makedonka Mitreva   +11 more
doaj   +2 more sources

Genetics of helminth infections: Immune system response, insights into host-parasite interaction, and drug resistance [PDF]

Journal of Advanced Veterinary and Animal Research
Helminthiases, which are caused by parasitic helminths, have a big effect on global health, especially in places with few resources. They cause a lot of illness and put a lot of strain on society and the economy.
Mashael Abdullah Aldamigh
doaj   +2 more sources

A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae [PDF]

, 2013
The aim of this study was to explore the mechanisms of resistance against invading Ascaris suum larvae in pigs. Pigs received a low dose of 100 A. suum eggs daily for 14 weeks.
Chiers, Koen, Geldhof, Peter, Masure, Dries, Van Den Broeck, Wim, Vercruysse, Jozef, Vlaminck, Johnny, Wang, Tao   +6 more
core   +34 more sources

Comprehensive Transcriptome Meta-analysis to Characterize Host Immune Responses in Helminth Infections. [PDF]

PLoS Neglected Tropical Diseases, 2016
Helminth infections affect more than a third of the world's population. Despite very broad phylogenetic differences among helminth parasite species, a systemic Th2 host immune response is typically associated with long-term helminth infections, also ...
Guangyan Zhou, Mary M Stevenson, Timothy G Geary, Jianguo Xia   +3 more
doaj   +1 more source

Evidence of MHC class I and II influencing viral and helminth infection via the microbiome in a non-human primate.

PLoS Pathogens, 2021
Until recently, the study of major histocompability complex (MHC) mediated immunity has focused on the direct link between MHC diversity and susceptibility to parasite infection.
B Karina Montero, Wasimuddin, Nina Schwensow, Mark A F Gillingham, Yedidya R Ratovonamana, S Jacques Rakotondranary, Victor Corman, Christian Drosten, Jörg U Ganzhorn, Simone Sommer   +9 more
doaj   +2 more sources