Results 31 to 40 of about 25,076 (227)

Haemonchus contortus P-glycoproteins interact with host eosinophil granules: a novel insight into the role of ABC transporters in host-parasite interaction. [PDF]

PLoS ONE, 2014
Eosinophils are one of the major mammalian effector cells encountered by helminths during infection. In the present study, we investigated the effects of eosinophil granule exposure on the sheep parasitic nematode Haemonchus contortus as a model.
Mohamed Issouf, Fabrice Guégnard, Christine Koch, Yves Le Vern, Alexandra Blanchard-Letort, Hua Che, Robin N Beech, Dominique Kerboeuf, Cedric Neveu   +8 more
doaj   +1 more source

Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. [PDF]

, 2006
Immunophilin is the collective name given to the cyclophilin and FK506-binding protein (FKBP) families. As the name suggests, these include the major binding proteins of certain immunosuppressive drugs: cyclophilins for the cyclic peptide cyclosporin A ...
Adams, Aliberti, Alphey, Angus Bell, Antony P. Page, Argaet, Banerjee, Banumathy, Belfiore, Bell, Bell, Bell, Berriman, Blumenthal, Blumenthal, Borel, Bozdech, Braun, Bua, Carlton, Chakraborty, Chakraborty, Chappell, Chappell, Cianciotto, Cohen, Colgan, Dao-Thi, Denkers, Dobson, Dolinski, Dornan, Dornan, Dutta, Fischer, Florens, Galat, Galat, Gavigan, Gavigan, Gilleard, Golding, Hacker, Hall, High, Hirtzlin, Hong, Hope, Kamath, Kay, Ke, Khattab, Kiang, Klinkert, Klinkert, Knobloch, Kumar, Kumar, Kumar, Le Roch, Lightowlers, Lorberg, Ma, Ma, Ma, Matsuda, McLauchlan, Mikol, Monaghan, Monaghan, Moro, Osman, Ostoa-Saloma, Oz, Page, Page, Page, Page, Page, Page, Page, Paul Monaghan, Pelle, Pereira, Peterson, Picken, Pratt, Rascher, Reddy, Riggs, Rossi, Shirane, Silverman, Taylor, Tuo, Valle, Wang, Weiwad, Williams, Yarovinsky, Yu, Zorio   +101 more
core   +1 more source

Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]

, 2011
Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Brüske, Irene, Flohrs, Katrin, Heinrich, Joachim, Rzehak, Peter, Thiering, Elisabeth, Wichmann, Heinz-Erich   +5 more
core   +1 more source

Helminth Microbiota Profiling Using Bacterial 16S rRNA Gene Amplicon Sequencing: From Sampling to Sequence Data Mining

, 2021
Symbiont microbial communities play important roles in animal biology and are thus considered integral components of metazoan organisms, including parasitic worms (helminths). Nevertheless, the study of helminth microbiomes has thus far been largely overlooked, and symbiotic relationships between helminths and their microbiomes have been only ...
Formenti, Fabio, Rinaldi, Gabriel, Cantacessi, Cinzia, Cortés, Alba   +3 more
openaire   +3 more sources

Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in Ghana.

PLoS Neglected Tropical Diseases, 2008
BackgroundHelminth infections are prevalent in rural areas of developing countries and have in some studies been negatively associated with allergic disorders and atopy.
Franca C Hartgers, Benedicta B Obeng, Yvonne C M Kruize, Marjolijn Duijvestein, Anna de Breij, Abena Amoah, Irene A Larbi, Ronald van Ree, Michael D Wilson, Laura C Rodrigues, Daniel A Boakye, Maria Yazdanbakhsh   +11 more
doaj   +1 more source

Effect of heterogeneous mixing and vaccination on the dynamics of anthelmintic resistance: a nested model. [PDF]

PLoS ONE, 2010
Anthelmintic resistance is a major threat to current measures for helminth control in humans and animals. The introduction of anthelmintic vaccines, as a complement to or replacement for drug treatments, has been advocated as a preventive measure.
Lorenzo Sabatelli
doaj   +1 more source

Enteric helminths promote Salmonella co-infection by altering the intestinal metabolome [PDF]

, 2017
Intestinal helminth infections occur pre dominantly in regions where exposure to enteric bacterial pathogens is also common. Helminth infections inhibit host immunity against microbial pathogens, which has largely been attributed to the induction of ...
Borchers, Christoph H., Brosschot, Tara P., Brown, Eric M., Finlay, B. Brett, Gill, Navkiran, Han, Jun, Marshall, Natalie C., Perona-Wright, Georgia, Redpath, Stephen A., Reynolds, Lisa A., Valdez, Yanet, van der Heijden, Joris, Woodward, Sarah E., Yurist-Doutsch, Sophie   +13 more
core   +1 more source

Antibodies trap tissue migrating helminth larvae and prevent tissue damage by driving IL-4Rα-independent alternative differentiation of macrophages.

PLoS Pathogens, 2013
Approximately one-third of the world's population suffers from chronic helminth infections with no effective vaccines currently available. Antibodies and alternatively activated macrophages (AAM) form crucial components of protective immunity against ...
Julia Esser-von Bieren, Ilaria Mosconi, Romain Guiet, Alessandra Piersgilli, Beatrice Volpe, Fei Chen, William C Gause, Arne Seitz, J Sjef Verbeek, Nicola L Harris   +9 more
doaj   +1 more source

Molecular phylogenetics and systematics of two enteric helminth parasites (Baylisascaris laevis and Diandrya vancouverensis) in the Vancouver Island marmot (Marmota vancouverensis)

International Journal for Parasitology: Parasites and Wildlife, 2022
Island biogeography can promote rapid diversification and speciation via geographic isolation and novel selection pressures. These same factors can threaten the persistence of island endemics by limiting gene flow and suitable habitat.
McIntyre A. Barrera, Jasmine K. Janes, Jamieson C. Gorrell   +2 more
doaj   +1 more source

CD4+ T cell hyporesponsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10 [PDF]

, 2015
The effect that multiple percutaneous exposures to Schistosoma larvae has on the development of early CD4+ lymphocyte reactivity is unclear, yet it is important in the context of humans living in areas where schistosomiasis is endemic.
Cook, Peter C., Mountford, Adrian P., Prendergast, Catriona T., Sanin, David E.   +3 more
core   +1 more source