Results 31 to 40 of about 12,335 (183)

Cytokine Gene Expression Profiles during HIV and Helminth Coinfection in Underprivileged Peri-Urban South African Adults

Diagnostics, 2023
Background: Intestinal helminth parasites are potent stimulators of T helper type 2 (Th2) and regulatory Th3 anti-inflammatory immune responses, while human immunodeficiency virus (HIV) infections are activators of predominantly T helper type 1(Th1) pro-inflammatory responses.
Miranda N. Mpaka-Mbatha, Pragalathan Naidoo, Khethiwe N. Bhengu, Md. Mazharul Islam, Ravesh Singh, Nomzamo Nembe-Mafa, Zilungile L. Mkhize-Kwitshana   +6 more
openaire   +3 more sources

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden.

PLoS Pathogens, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Jessica C Jang, Gang Chen, Spencer H Wang, Mark A Barnes, Josiah I Chung, Mali Camberis, Graham Le Gros, Philip J Cooper, Cathy Steel, Thomas B Nutman, Mitchell A Lazar, Meera G Nair   +11 more
doaj   +1 more source

Relationship between NRAMP1 gene polymorphism and efficacy of BCG vaccine in helminth-infected populations

Genetics and Molecular Research, 2013
Infection of mothers with schistosomiasis and filariasis has been shown to influence infant responses to neonatal Bacille Calmette-Guérin (BCG) immunization. The genetic makeup of infants is also considered an important determinant for the activity of BCG vaccine.
A A, Badawy, R S, Yahya, S I, Awad, G A, Al-Sawah, N A, Kizilbash   +4 more
openaire   +2 more sources

Genetic parameters of infectious bovine keratoconjunctivitis and its relationship with weight and parasite infestations in Australian tropical Bos taurus cattle

Genetics Selection Evolution, 2012
Background Infectious bovine keratoconjunctivitis (IBK) or ‘pinkeye’ is an economically important ocular disease that significantly impacts animal performance.
Ali Abdirahman A, O’Neill Christopher J, Thomson Peter C, Kadarmideen Haja N   +3 more
doaj   +1 more source

Genomic analyses of aminoacyl tRNA synthetases from human-infecting helminths

BMC Genomics, 2019
Background Helminth infections affect ~ 60% of the human population that lives in tropical and subtropical regions worldwide. These infections result in diseases like schistosomiasis, lymphatic filariasis, river blindness and echinococcosis.
Preeti Goel, Suhel Parvez, Amit Sharma
doaj   +1 more source

Mmp17-deficient mice exhibit heightened goblet cell effector expression in the colon and increased resistance to chronic Trichuris muris infection

Frontiers in Immunology, 2023
Intestinal epithelial homeostasis is maintained by intrinsic and extrinsic signals. The extrinsic signals include those provided by mesenchymal cell populations that surround intestinal crypts and is further facilitated by the extracellular matrix (ECM),
Pia M. Vornewald, Ruth Forman, Rouan Yao, Naveen Parmar, Håvard T. Lindholm, Lilith S. K. Lee, Mara Martín-Alonso, Kathryn J. Else, Menno J. Oudhoff, Menno J. Oudhoff   +9 more
doaj   +1 more source

Single-Nucleotide Polymorphisms in the Beta-Tubulin Gene and Its Relationship with Treatment Response to Albendazole in Human Soil-Transmitted Helminths in Southern Mozambique

The American Journal of Tropical Medicine and Hygiene, 2022
ABSTRACT. Soil-transmitted helminth (STH) cornerstone control strategy is mass drug administration (MDA) with benzimidazoles. However, MDA might contribute to selection pressure for anthelmintic resistance, as occurred in livestock. The aim of this study is to evaluate the treatment response to albendazole and the relationship with the presence of ...
Berta Grau-Pujol, Javier Gandasegui, Valdemiro Escola, Helena Marti‐Soler, María Cambra-Pellejà, Maria Antonietta Demontis, Eric A. T. Brienen, José Carlos Jamine, Osvaldo Muchisse, Anélsio Cossa, Charfudin Sacoor, Jorge Cano, Lisette van Lieshout, María Martínez Valladares, José Muñóz   +14 more
openaire   +5 more sources

Finite element analysis of feeding in red and gray squirrels (Sciurus vulgaris and Sciurus carolinensis)

The Anatomical Record, EarlyView.
Abstract Invasive gray squirrels (Sciurus carolinensis) have replaced the native red squirrel (Sciurus vulgaris) across much of Great Britain over the last century. Several factors have been proposed to underlie this replacement, but here we investigated the potential for dietary competition in which gray squirrels have better feeding performance than ...
Philip G. Cox, Peter J. Watson
wiley   +1 more source

Virome remodeling rewires epigenetic and metabolic pathways linked to infection-associated colorectal cancer risk

Aspects of Molecular Medicine
Background: Colorectal cancer (CRC) incidence is rising in sub-Saharan Africa, coinciding with the high prevalence of immune-modulating infections such as HIV and helminths.
Botle Precious Damane, Jonathan Featherston, Shakeel Kader, Mohammed Alaouna, Pragalathan Naidoo, Zodwa Dlamini, Zilungile Lynette Mkhize-Kwitshana   +6 more
doaj   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source