Results 41 to 50 of about 25,076 (227)
Searching for antigen B genes and their adaptive sites in distinct strains and species of the helminth Echinococcus [PDF]
Infection, Genetics and Evolution, 2006 Twenty-seven PCR-derived antigen B (AgB) nucleotide sequences from four Echinococcus species (Echinococcus granulosus, Echinococcus multilocularis, Echinococcus oligarthrus and Echinococcus vogeli) were aligned with 78 already published sequences, to generate a maximum likelihood phylogeny of the AgB multigene family. The phylogenetic analysis confirms
Haag, KL +5 more
openaire +4 more sources
The Immune and Non-Immune Pathways That Drive Chronic Gastrointestinal Helminth Burdens in the Wild
Frontiers in Immunology, 2018 Parasitic helminths are extremely resilient in their ability to maintain chronic infection burdens despite (or maybe because of) their hosts’ immune response.
Simon A. Babayan +6 more
doaj +1 more source
Genetics and Molecular Research, 2013 Infection of mothers with schistosomiasis and filariasis has been shown to influence infant responses to neonatal Bacille Calmette-Guérin (BCG) immunization. The genetic makeup of infants is also considered an important determinant for the activity of BCG vaccine.
A A, Badawy +4 more
openaire +2 more sources
Promoter haplotypes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen [PDF]
Genes & Immunity, 2004 Since interleukin (IL)-10 is a key mediator of immunosuppression, and immunosuppression is considered an important element of helminth infection, we studied variants of the putative IL-10 gene promoter in 337 individuals from 130 families heavily exposed to infection by the tissue nematode Onchocerca volvulus.
C, Timmann +8 more
openaire +2 more sources
Impact of Experimental Hookworm Infection on the Human Gut Microbiota [PDF]
, 2014 The interactions between gastrointestinal parasitic helminths and commensal bacteria are likely to play a pivotal role in the establishment of host-parasite cross-talk, ultimately shaping the development of the intestinal immune system.
Alex Loukas +24 more
core +3 more sources
Genetics Selection Evolution, 2012 Background Infectious bovine keratoconjunctivitis (IBK) or ‘pinkeye’ is an economically important ocular disease that significantly impacts animal performance.
Ali Abdirahman A +3 more
doaj +1 more source
Frontiers in Immunology, 2023 Intestinal epithelial homeostasis is maintained by intrinsic and extrinsic signals. The extrinsic signals include those provided by mesenchymal cell populations that surround intestinal crypts and is further facilitated by the extracellular matrix (ECM),
Pia M. Vornewald +9 more
doaj +1 more source
Identifcation of small molecule enzyme inhibitors as broad-spectrum anthelmintics [PDF]
, 2019 Targeting chokepoint enzymes in metabolic pathways has led to new drugs for cancers, autoimmune disorders and infectious diseases. This is also a cornerstone approach for discovery and development of anthelmintics against nematode and flatworm parasites.
Aroian, Raffi V. +10 more
core +3 more sources
Genomic analyses of aminoacyl tRNA synthetases from human-infecting helminths
BMC Genomics, 2019 Background Helminth infections affect ~ 60% of the human population that lives in tropical and subtropical regions worldwide. These infections result in diseases like schistosomiasis, lymphatic filariasis, river blindness and echinococcosis.
Preeti Goel, Suhel Parvez, Amit Sharma
doaj +1 more source
Comparative genetic resistance to Ascaridia galli infections of 4 different commercial layer-lines [PDF]
, 2003 1. The objective of the study was to compare the establishment and effect of Ascaridia galli infections in 4 different layer-lines. 2. A total of 160 birds comprising 4 different commercial layer-lines, ISA Brown, New Hampshire, Skalborg and a cross of ...
Kjaer, J. +4 more
core +1 more source