Results 51 to 60 of about 25,076 (227)

A Novel Non-invasive Method to Detect RELM Beta Transcript in Gut Barrier Related Changes During a Gastrointestinal Nematode Infection [PDF]

open access: yes, 2019
Currently, methods for monitoring changes of gut barrier integrity and the associated immune response via non-invasive means are limited. Therefore, we aimed to develop a novel non-invasive technique to investigate immunological host responses ...
Affinass, Nicole   +8 more
core   +4 more sources

Local cytokine transcription in naïve and previously infected sheep and lambs following challenge with Teladorsagia circumcincta [PDF]

open access: yes, 2014
<b>Background</b><p></p> The abomasal helminth Teladorsagia circumcincta is one of the most economically important parasites affecting sheep in temperate regions.
Craig, Nicola M   +4 more
core   +3 more sources

Helminths in the gastrointestinal tract 1 as modulators of immunity and pathology [PDF]

open access: yes, 2017
Helminth parasites are highly prevalent in many low- and middle-income countries, in which inflammatory bowel disease and other immunopathologies are less frequent than in the developed world.
Fleming, John O.   +2 more
core   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

Virome remodeling rewires epigenetic and metabolic pathways linked to infection-associated colorectal cancer risk

open access: yesAspects of Molecular Medicine
Background: Colorectal cancer (CRC) incidence is rising in sub-Saharan Africa, coinciding with the high prevalence of immune-modulating infections such as HIV and helminths.
Botle Precious Damane   +6 more
doaj   +1 more source

Parasite-Probiotic Interactions in the Gut: Bacillus sp. and Enterococcus faecium Regulate Type-2 Inflammatory Responses and Modify the Gut Microbiota of Pigs During Helminth Infection

open access: yesFrontiers in Immunology, 2022
Dietary probiotics may enhance gut health by directly competing with pathogenic agents and through immunostimulatory effects. These properties are recognized in the context of bacterial and viral pathogens, but less is known about interactions with ...
Laura J. Myhill   +11 more
doaj   +1 more source

The tapeworm interactome: inferring confidence scored protein-protein interactions from the proteome of Hymenolepis microstoma [PDF]

open access: yes, 2020
BACKGROUND: Reference genome and transcriptome assemblies of helminths have reached a level of completion whereby secondary analyses that rely on accurate gene estimation or syntenic relationships can be now conducted with a high level of confidence ...
James, Katherine, Olson, Peter D.
core   +2 more sources

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

open access: yesAdvanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao   +11 more
wiley   +1 more source

Genes associated with alternatively activated macrophages discretely regulate helminth infection and pathogenesis in experimental mouse models

open access: yesImmunobiology, 2010
Resolution of helminth infections is typically associated with the host launching a TH2 dominated immune response. In experimental models of helminth infections a key feature of this TH2 immunity is the induction of alternatively activated macrophage (AAM) populations.
William G C, Horsnell, Frank, Brombacher
openaire   +2 more sources

Placental gene expression and antibody levels of mother-neonate pairs reveal an enhanced risk for inflammation in a helminth endemic country [PDF]

open access: yesScientific Reports, 2019
AbstractIn uteroexposure to environmental factors can modify the development of allergies later in life whereby the mechanisms of the feto-maternal crosstalk still remain largely unknown. Murine studies revealed that inflammatory maternal signals elicited by chronic helminth infection within the placenta imprint a distinct gene expression profile ...
Ludwig, E.   +11 more
openaire   +4 more sources

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