Results 71 to 80 of about 304,068 (299)

Paving the Way to Elucidate Hg's Role in Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li   +10 more
wiley   +1 more source

Innate Immunity in C. elegans [PDF]

open access: yes, 2010
The nematode Caenorhabditis elegans is proving to be a powerful invertebrate model to study host-pathogen interactions. In common with other invertebrates, C. elegans relies solely on its innate immune system to defend itself against pathogens. Studies of the nematode response to infection with various fungal and bacterial pathogens have revealed that ...
Ilka, Engelmann, Nathalie, Pujol
openaire   +5 more sources

Selenite enhances immune response against Pseudomonas aeruginosa PA14 via SKN-1 in Caenorhabditis elegans. [PDF]

open access: yesPLoS ONE, 2014
Selenium (Se) is an important nutrient that carries out many biological processes including maintaining optimal immune function. Here, inorganic selenite (Se(IV)) was evaluated for its pathogen resistance and potential-associated factors in ...
Wen-Hsuan Li   +4 more
doaj   +1 more source

Caenorhabditis elegans and probiotics interactions from a prolongevity perspective [PDF]

open access: yes, 2019
Probiotics exert beneficial effects on host health through different mechanisms of action, such as production of antimicrobial substances, competition with pathogens, enhancement of host mucosal barrier integrity and immunomodulation.
Barbara Guantario   +5 more
core   +1 more source

Chemosensation in C. elegans [PDF]

open access: yesWormBook, 2006
C. elegans has a highly developed chemosensory system that enables it to detect a wide variety of volatile (olfactory) and water-soluble (gustatory) cues associated with food, danger, or other animals. Much of its nervous system and more than 5% of its genes are devoted to the recognition of environmental chemicals.
openaire   +2 more sources

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

An evolutionarily conserved transcriptional response to viral infection in Caenorhabditis nematodes

open access: yesBMC Genomics, 2017
Background Caenorhabditis elegans is a powerful model organism for probing many biological processes including host-pathogen interactions with bacteria and fungi. The recent identification of nematode viruses that naturally infect C.
Kevin Chen   +4 more
doaj   +1 more source

Characterization of aminopeptidase encoding gene anp-1 and its association with development in Caenorhabditis elegans [PDF]

open access: yesPeerJ, 2019
Background Aminopeptidases play important roles in various biological processes in nematodes including growth, development and reproduction. Although the aminopeptidases have been shown to regulate reproduction in Caenorhabditis elegans (C. elegans), the
Shanchun Su   +3 more
doaj   +2 more sources

Characterization of the Ca2+-gated and voltage-dependent k+-channel slo-1 of nematodes and its interaction with emodepside [PDF]

open access: yes, 2014
The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-spectrum nematicidal drugs which are able to eliminate nematodes resistant to other anthelmintics.
Ballesteros, Cristina   +11 more
core   +6 more sources

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

open access: yesAdvanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei   +17 more
wiley   +1 more source

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