Results 51 to 60 of about 133,009 (166)

Metabolic labeling of Caenorhabditis elegans primary embryonic cells with azido-sugars as a tool for glycoprotein discovery. [PDF]

open access: yesPLoS ONE, 2012
Glycobiology research with Caenorhabditis elegans (C. elegans) has benefitted from the numerous genetic and cell biology tools available in this system. However, the lack of a cell line and the relative inaccessibility of C. elegans somatic cells in vivo
Amanda R Burnham-Marusich   +6 more
doaj   +1 more source

Determinants in the LIN-12/Notch Intracellular Domain That Govern Its Activity and Stability During Caenorhabditis elegans Vulval Development

open access: yesG3: Genes, Genomes, Genetics, 2016
Upon ligand binding, the LIN-12/Notch intracellular domain is released from its transmembrane tether to function in a nuclear complex that activates transcription of target genes.
Yuting Deng, Iva Greenwald
doaj   +1 more source

Isolation of specific neurons from C. elegans larvae for gene expression profiling. [PDF]

open access: yesPLoS ONE, 2014
The simple and well-described structure of the C. elegans nervous system offers an unprecedented opportunity to identify the genetic programs that define the connectivity and function of individual neurons and their circuits.
W Clay Spencer   +7 more
doaj   +1 more source

Poly-G/poly-C tracts in the genomes of Caenorhabditis

open access: yesBMC Genomics, 2007
Background In the genome of Caenorhabditis elegans, homopolymeric poly-G/poly-C tracts (G/C tracts) exist at high frequency and are maintained by the activity of the DOG-1 protein. The frequency and distribution of G/C tracts in the genomes of C. elegans
Rose Ann M, O'Neil Nigel J, Zhao Yang
doaj   +1 more source

Impaired immune response and barrier function in GSPD-1-deficient C. elegans infected with Klebsiella pneumoniae

open access: yesCurrent Research in Microbial Sciences, 2023
gspd-1-RNAi knockdown Caenorhabditis elegans was used as an immune-compromised model to investigate the role of G6PD in host-pathogen interactions.
Wan-Hua Yang   +7 more
doaj   +1 more source

A Game-Theoretical Network Formation Model for C. elegans Neural Network

open access: yesFrontiers in Computational Neuroscience, 2019
Studying and understanding human brain structures and functions have become one of the most challenging issues in neuroscience today. However, the mammalian nervous system is made up of hundreds of millions of neurons and billions of synapses.
Mohamad Khajezade   +2 more
doaj   +1 more source

Axon regeneration in C. elegans [PDF]

open access: yesCurrent Opinion in Neurobiology, 2014
Single axon transection by laser surgery has made Caenorhabditis elegans a new model for axon regeneration. Multiple conserved molecular signaling modules have been discovered through powerful genetic screening. In vivo imaging with single cell and axon resolution has revealed unprecedented cellular dynamics in regenerating axons.
Hammarlund, Marc, Jin, Yishi
openaire   +4 more sources

The Microbial Zoo in the C. elegans Intestine: Bacteria, Fungi and Viruses

open access: yesViruses, 2018
C. elegans is an invaluable model organism that has been a driving force in many fundamental biological discoveries. However, it is only in the past two decades that it has been applied to host–pathogen interaction studies.
Hongbing Jiang, David Wang
doaj   +1 more source

Selenite enhances immune response against Pseudomonas aeruginosa PA14 via SKN-1 in Caenorhabditis elegans. [PDF]

open access: yesPLoS ONE, 2014
Selenium (Se) is an important nutrient that carries out many biological processes including maintaining optimal immune function. Here, inorganic selenite (Se(IV)) was evaluated for its pathogen resistance and potential-associated factors in ...
Wen-Hsuan Li   +4 more
doaj   +1 more source

Neuropeptide GPCRs in C. elegans [PDF]

open access: yesFrontiers in Endocrinology, 2012
Like most organisms, the nematode Caenorhabditis elegans relies heavily on neuropeptidergic signaling. This tiny animal represents a suitable model system to study neuropeptidergic signaling networks with single cell resolution due to the availability of powerful molecular and genetic tools.
Frooninckx, Lotte   +7 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy