Results 31 to 40 of about 304,068 (299)
Soil nematode Caenorhabditis elegans Maupas as a convenient model organism to study anthelmintic activity of plant extracts [PDF]
The article deals with the study of the possibility to use free-living soil nematode C. elegans in researches of anthelmintic activity of plant raw material. A. sativum juice and aqueous extract of T. vulgare flowers were used in experiments. It is shown
Egorova Anastasia +4 more
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To use Caenorhabditis elegans to study the mechanisms for initiation and execution of necrosis, the experimentalist should be familiar with the established models of necrosis in C. elegans and the genetic and molecular tools available. We present a summary of two contrasting models for studying necrosis in C. elegans and outline the methods for scoring
Matt, Crook +2 more
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Inappropriateness of RNAlater to preserve Caenorhabditis elegans for RNA extraction
Caenorhabditis elegans is a well-established laboratory animal model and has been widely used in biological research. However, it is still a challenge to obtain a good amount of quality RNA from a limited number of C. elegans for gene expression studies.
Leming Jiang +6 more
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A Pipeline for Volume Electron Microscopy of the Caenorhabditis elegans Nervous System. [PDF]
The "connectome," a comprehensive wiring diagram of synaptic connectivity, is achieved through volume electron microscopy (vEM) analysis of an entire nervous system and all associated non-neuronal tissues. White et al.
Chisholm, Andrew D +7 more
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Growth of Caenorhabditis elegans in Defined Media Is Dependent on Presence of Particulate Matter
Caenorhabditis elegans are typically cultured in a monoxenic medium consisting of live bacteria. However, this introduces a secondary organism to experiments, and restricts the manipulation of the nutritional environment.
Matthew R. Flavel +12 more
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Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response. [PDF]
The progressive failure of protein homeostasis is a hallmark of aging and a common feature in neurodegenerative disease. As the enzymes executing the final stages of autophagy, lysosomal proteases are key contributors to the maintenance of protein ...
Ashrafi, Kaveh +10 more
core +1 more source
WormBase: a comprehensive resource for nematode research [PDF]
WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evolved into a powerful research tool in its own right.
Antoshechkin, Igor +31 more
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Gap junctions in C. elegans [PDF]
As in other multicellular organisms, the nematode Caenorhabditis elegans uses gap junctions to provide direct cell-to-cell contact. The nematode gap junctions are formed by innexins (invertebrate analogs of the connexins); a family of proteins that surprisingly share no primary sequence homology, but do share structural and functional similarity with ...
Karina eSimonsen +3 more
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The C. elegans intestine [PDF]
The intestine is one of the major organs in C. elegans and is largely responsible for food digestion and assimilation as well as the synthesis and storage of macromolecules. In addition, the intestine is emerging as a powerful experimental system in which to study such universal biological phenomena as vesicular trafficking, biochemical clocks, stress ...
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Transient receptor potential (TRP) channels represent a superfamily of cation channels found in all eukaryotes. The C. elegans genome encodes seventeen TRP channels covering all of the seven TRP subfamilies. Genetic analyses in C. elegans have implicated TRP channels in a wide spectrum of behavioral and physiological processes, ranging from sensory ...
Rui, Xiao, X Z Shawn, Xu
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