Results 21 to 30 of about 18,831,157 (296)
Gap junctions in C. elegans [PDF]
Frontiers in Physiology, 2014 As in other multicellular organisms, the nematode Caenorhabditis elegans uses gap junctions to provide direct cell-to-cell contact. The nematode gap junctions are formed by innexins (invertebrate analogs of the connexins); a family of proteins that surprisingly share no primary sequence homology, but do share structural and functional similarity with ...
Karina eSimonsen +3 more
openaire +3 more sources
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
Mechanisms of microRNA mediated gene silencing in C. elegans [PDF]
, 2009 Mechanisms of microRNA mediated gene silencing in C. elegans Xavier Ding Dissertation abstract microRNAs (miRNAs) are a large family of small non-coding RNAs, which post-transcriptionally repress numerous genes; a type of regulation which is ...
Ding, Xavier
core +1 more source
The C. elegans intestine [PDF]
WormBook, 2007 The intestine is one of the major organs in C. elegans and is largely responsible for food digestion and assimilation as well as the synthesis and storage of macromolecules. In addition, the intestine is emerging as a powerful experimental system in which to study such universal biological phenomena as vesicular trafficking, biochemical clocks, stress ...
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Developmental Cell, 2003 To gain insights into the genetic cascades that regulate fat biology, we evaluated C. elegans as an appropriate model organism. We generated worms that lack two transcription factors, SREBP and C/EBP, crucial for formation of mammalian fat. Worms deficient in either of these genes displayed a lipid-depleted phenotype-pale, skinny, larval-arrested worms
McKay, Renée M. +3 more
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Regulation of the maternal-to-embryonic transition in "C. elegans" [PDF]
, 2012 Reproduction is a fundamental process of life which allows the survival of each species through the birth of young species members. Several modes of reproduction evolved and are classified into sexual and asexual reproduction.
Finger, Susanne
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Mathematical Models of the Developing C. elegans Hermaphrodite Gonad [PDF]
, 2006 The study of growing and developing organisms is a fascinating branch of experimental biology. Once created, cells must exchange chemical and physical cues with neighboring cells in order to grow, divide, and differentiate properly.
Goulet, David Michael
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High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection. [PDF]
PLoS ONE, 2008 We present a novel strategy that uses high-throughput methods of isolating and mapping C. elegans mutants susceptible to pathogen infection. We show that C.
Laura E Fuhrman +2 more
doaj +1 more source
Microbial light-activatable proton pumps as neuronal inhibitors to functionally dissect neuronal networks in C. elegans [PDF]
, 2012 Essentially any behavior in simple and complex animals depends on neuronal network function. Currently, the best-defined system to study neuronal circuits is the nematode Caenorhabditis elegans, as the connectivity of its 302 neurons is exactly known ...
Hang Lu (151732) +17 more
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On-Demand Isolation and Manipulation of C. elegans by In Vitro Maskless Photopatterning. [PDF]
PLoS ONE, 2016 Caenorhabditis elegans (C. elegans) is a model organism for understanding aging and studying animal behavior. Microfluidic assay techniques have brought widespread advances in C.
C Ryan Oliver +4 more
doaj +1 more source