Results 21 to 30 of about 33,016 (225)

Low Diversity Cryptococcus neoformans Variety grubii Multilocus Sequence Types from Thailand Are Consistent with an Ancestral African Origin [PDF]

, 2011
The global burden of HIV-associated cryptococcal meningitis is estimated at nearly one million cases per year, causing up to a third of all AIDS-related deaths.
Fisher, M.D., Annemarie E. Brouwer, Thomas S Harrison, Simwami, SP, Matthew C Fisher, Boekhout, T, Khayhan Kantarawee, Aanensen, D.M., Brouwer Annemarie E., Hagen, F, Daniel A Henk, Matthew C. Fisher, Harrison, T.S., Henk Daniel A., Donnelly Christl A., Harrison Thomas S., Fisher Matthew C., Khayhan, K., David M. Aanensen, Aanensen David M., Annemarie E Brouwer, Brouwer, A.E., Donnelly, C.A., Aanensen, DM, Christl A Donnelly, Henk, DA, Brouwer, AE, Hagen, F., Henk, D.A., Sitali P. Simwami, Sitali P Simwami, Khayhan, K, Donnelly, CA, Ferry Hagen, Daniel A. Henk, Fisher, MC, Christl A. Donnelly, Teun Boekhout, Hagen Ferry, Kantarawee Khayhan, Simwami Sitali P., Boekhout, T., Boekhout Teun, Harrison, TS, Thomas S. Harrison, Simwami, S.P., David M Aanensen   +46 more
core   +1 more source

Immune evasion by Cryptococcus gattii in vaccinated mice coinfected with C. neoformans. [PDF]

Front Immunol
Cryptococcus neoformans and C. gattii, the etiologic agents of cryptococcosis, cause over 100,000 deaths worldwide every year, yet no cryptococcal vaccine has progressed to clinical trials. In preclinical studies, mice vaccinated with an attenuated strain of C.
Hester MM, Carlson D, Lodge JK, Levitz SM, Specht CA.   +4 more
europepmc   +4 more sources

Subculturing and Gram staining of blood cultures flagged negative by the BACTEC™ FX system: Optimizing the workflow for detection of Cryptococcus neoformans in clinical specimens

Frontiers in Microbiology, 2023
ObjectiveTo investigate whether an incubation time of 5 days (Aerobic/F, Anaerobic/F) and 14 days (Myco/F) blood culture bottles is sufficient to prevent false-negative results.MethodsWe evaluated 1,244 blood bottles (344 patients) defined as negative by
Lingli Liu, Lingli Liu, Lijun Du, Lijun Du, Lijun Du, Shuquan He, Shuquan He, Shuquan He, Tianshu Sun, Fanrong Kong, Yali Liu, Yali Liu, Yali Liu, Yingchun Xu, Yingchun Xu   +14 more
doaj   +1 more source

Capsule independent uptake of the fungal pathogen Cryptococcus neoformans into brain microvascular endothelial cells. [PDF]

, 2012
Cryptococcosis is a life-threatening fungal disease with a high rate of mortality among HIV/AIDS patients across the world. The ability to penetrate the blood-brain barrier (BBB) is central to the pathogenesis of cryptococcosis, but the way in which this
May, Robin C, Wilber Sabiiti (170648), Sabiiti, Wilber, May, Robin; id_orcid, Sabiiti, W, May, RC, Robin C. May (170650), Wilber Sabiiti, Sabiiti Wilber, Robin C May, May Robin C.   +10 more
core   +1 more source

Genotypic diversity is associated with clinical outcome and phenotype in cryptococcal meningitis across Southern Africa [PDF]

, 2015
This work was supported by Wellcome Trust (UK) (www.wellcome.ac.uk) awards to TB (WT069991), GM (WT098316), and JNJ (WT081794); Medical Research Council (MRC UK) (www.mrc.ac.uk) awards to MCF (K000373/1), RCM (G0601171), TSH (G1002327); European Research
Fisher, Matthew C, Matthew C Fisher, Matthew C. Fisher (129755), Angela Loyse (292490), Meintjes, Graeme, Fisher, Matthew C., Emma J. Robertson (760738), Sabiiti, Wilber, O'Hanlon, SJ, O'Hanlon, Simon J, Joseph N Jarvis, Tihana Bicanic (718812), Thomas S. Harrison (222993), Fisher, MC, Karen M Fuentes-Cabrejo, Fuentes-Cabrejo, KM, Fuentes-Cabrejo, Karen M, Angela Loyse, Fisher, M, Harrison, Thomas S, Harrison, TS, Robertson, EJ, Simon J. O’Hanlon (760740), Loyse, Angela, Meintjes, G, Simon J O'Hanlon, Robin C May, Jarvis, Joseph N, Emma J Robertson, Wilber Sabiiti (170648), Thomas S Harrison, Mathew A. Beale (663616), Wilber Sabiiti, Robertson, Emma J, Joseph N. Jarvis (435279), Robertson, Emma J., Jarvis, JN, May, Robin C, Mathew A Beale, Karen M. Fuentes-Cabrejo (760739), Graeme Meintjes (221054), Beale, Mathew A, Tihana Bicanic, Sabiiti, W, Bicanic, T, May, RC, Loyse, A, May, Robin C; id_orcid, Bicanic, Tihana, Graeme Meintjes, Beale, MA, Robin C. May (170650)   +51 more
core   +1 more source

Phospholipids trigger Cryptococcus neoformans capsular enlargement during interactions with amoebae and macrophages. [PDF]

PLoS Pathogens, 2011
A remarkable aspect of the interaction of Cryptococcus neoformans with mammalian hosts is a consistent increase in capsule volume. Given that many aspects of the interaction of C.
Cara J Chrisman, Patricia Albuquerque, Allan J Guimaraes, Edward Nieves, Arturo Casadevall   +4 more
doaj   +1 more source

State of the Field: Cytotoxic Immune Cell Responses in C. neoformans and C. deneoformans Infection. [PDF]

J Fungi (Basel)
Cryptococcus neoformans is an environmental pathogen that causes life-threatening disease in immunocompromised persons. The majority of immunological studies have centered on CD4+ T-cell dysfunction and associated cytokine signaling pathways, optimization of phagocytic cell function against fungal cells, and identification of robust antigens for ...
Okafor EC, Nielsen K.
europepmc   +4 more sources

Pulmonary Iron Limitation Induced by Exogenous Type I IFN Protects Mice from Cryptococcus gattii Independently of T Cells

mBio, 2019
Cryptococcus neoformans causes deadly mycosis primarily in AIDS patients, whereas Cryptococcus gattii infects mostly non-HIV patients, even in regions with high burdens of HIV/AIDS and an established environmental presence of C. gattii.
Michael J. Davis, Shannon Moyer, Elizabeth S. Hoke, Edward Sionov, Katrin D. Mayer-Barber, Dan L. Barber, Hongyi Cai, Lisa Jenkins, Peter J. Walter, Yun C. Chang, Kyung J. Kwon-Chung   +10 more
doaj   +1 more source

FertileCryptococcus neoformansvar.neoformans(C. deneoformans) isolates from natural environment in Kosovo

Medical Mycology, 2023
AbstractA total of 300 tree-associated samples were collected from green areas in three towns in Kosovo, and cultured to isolate Cryptococcus species. One soil sample from Prizren tested positive, yielding three isolates identified as C. neoformans var. neoformans (C. deneoformans), molecular type VNIV, two MATα, and one MATa.
Pllana-Hajdari, Donjeta, Chidebelu, Ekene P, Cogliati, Massimo   +2 more
openaire   +3 more sources

Quimiotipagem do Cryptococcus neoformans. Revisão da literatura. Novos dados epidemiológicos sobre a criptococose. Nossa experiência com o emprego do meio de C.G.B. no estudo daquela levedura Biotyping of Cryptococcus neoformans. Review of the literature. New epidemiologic informations about cryptococcosis. Our experience with the utilization of C.G.B medium in this yeast

Revista do Instituto de Medicina Tropical de São Paulo, 1993
O presente trabalho, além da revisão da literatura sobre quimiotipagem do C. neoformans, com novos dados sobre a epidemiologia da criptococose, teve por finalidade principal a caracterização das duas variedades desta levedura em pacientes com ...
Natalina Takahashi de Melo, Carlos da Silva Lacaz, Cecília Eugênia Charbel, Amélia Dias Pereira, Elisabeth Maria Heins-Vaccari, Antonio Spina França-Netto, Luis dos Ramos Machado, José Antonio Livramento   +7 more
doaj   +1 more source