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Cryptococcus neoformans var. neoformans is the second most prevalent agent of cryptococcosis in central Europe. Infections mostly present with localized skin and disseminated infections.
Zena M. Birkenfeld +5 more
doaj +1 more source
Amoeba resistance QTL for C. neoformans and C. deneoformans.
A. Manhattan plot representing the association between genotype and amoeba resistance in the C. neoformans mapping populations. The dotted line indicates the significance threshold by permutation. B.
Sheng Sun (142836) +8 more
core +1 more source
The Role of Ceramide Synthases in the Pathogenicity of Cryptococcus neoformans
Summary: Cryptococcus neoformans (C. neoformans) is estimated to cause about 220,000 new cases every year in patients with AIDS, despite advances in antifungal treatments. C.
Mansa A. Munshi +7 more
doaj +1 more source
Cryptococcus neoformans is a basidiomycete fungus capable of causing deadly meningoenchephilitis, primarily in immunocompromised individuals. Formerly, C. neoformans was composed of two divergent lineages, but these have recently been elevated to species
Aaron A. Vogan +3 more
doaj +1 more source
Synthesis of a hexasaccharide fragment of the O-deacetylated GXM of C. neoformans serotype B [PDF]
beta-D-Xylp-(1-->4)-alpha-D-Manp-(1-->3)-[beta-D-Xylp-(1-->2)]-alpha-D-Manp-(1-->3)-[beta-D-Xylp-(1-->2)]-alpha-D-Manp, the fragment of the exopolysaccharide from Cryptococcus neoformans serovar B, was synthesized as its methyl glycoside. Thus, acetylation of allyl 3-O-benzoyl-4,6-O-benzylidene-alpha-D-mannopyranoside (1) followed by debenzylidenation ...
Wei, Zhao, Fanzuo, Kong
openaire +4 more sources
Cryptococcus neoformans isolation from swallow (Hirundo rustica) excreta in Iran
Cryptococcus neoformans is an encapsulated yeast that can cause cryptococcosis, a life-threatening infection that mainly occurs in immunocompromised patients. The major environmental sources of C.
Mohammad T. Hedayati +4 more
doaj +1 more source
Macropinocytosis as a potential mechanism driving neurotropism of Cryptococcus neoformans
Cryptococcus neoformans can invade the central nervous system by crossing the blood-brain barrier via a transcellular mechanism that relies on multiple host factors. In this narrative, we review the evidence that a direct interplay between C.
Dylan M. Lanser +3 more
doaj +1 more source
Autophagy is mainly a catabolic process, which is used to cope with nutrient deficiency and various stress conditions. Human environment often imposes various stresses on Cryptococcus neoformans, a major fungal pathogen of immunocompromised individuals ...
Xueru Zhao +7 more
doaj +1 more source
Amoeba resistance varies between strains of C. neoformans.
A. A schematic overview of the amoeba resistance assay. A lawn of Cryptococcus is grown on V8 media for 60 hours. A. castellanii are added to the center of the lawn. A.
Sheng Sun (142836) +8 more
core +1 more source
Cryptococcus neoformans modulates extracellular killing by neutrophils
We recently established a key role for host sphingomyelin synthase (SMS) in the regulation of the killing activity of neutrophils against Cryptococcus neoformans. In this work, we studied the effect of C. neoformans on the killing activity of neutrophils
Asfia eQureshi +4 more
doaj +1 more source

