Results 11 to 20 of about 56,587 (222)

C. tropicalis promotes CRC by down-regulating tumor cell-intrinsic PD-1 receptor via autophagy. [PDF]

open access: yesJ Cancer, 2023
Background: The programmed cell death 1 (PD-1) receptor is an immune checkpoint molecule that induces immune tolerance and mediates the immune escape of tumor cells. It is mainly expressed in immune cells such as T cells, B cells and monocytes. In recent years, studies have shown that tumor cell-intrinsic PD-1 plays different roles in the development ...
Qu J   +6 more
europepmc   +3 more sources

Virulence Factors and Antifungal Susceptibility Profile of C. tropicalis Isolated from Various Clinical Specimens in Alexandria, Egypt. [PDF]

open access: yesJ Fungi (Basel), 2021
Background: The incidence of candidiasis caused by non-albicans Candida (NAC) species is increasing. Candida tropicalis has emerged as one of the most important NAC species. This study aims to examine the antifungal susceptibility profile and some virulence factors of C. tropicalis isolated from various clinical specimens.
El-Kholy MA   +4 more
europepmc   +5 more sources

Azole and echinocandin resistance mechanisms and genotyping of Candida tropicalis in Japan: cross-boundary dissemination and animal–human transmission of C. tropicalis infection [PDF]

open access: yesClinical Microbiology and Infection, 2022
To assess the prevalence and genetic basis of antifungal resistance mechanisms as well as the genotyping of Candida tropicalis from clinical and non-clinical sources in Japan.Eighty C. tropicalis isolates, including 32 clinical isolates recovered from 29 patients and 48 non-clinical isolates recovered from 24 different sources (animals and the ...
Hazim O, Khalifa   +2 more
openaire   +2 more sources

Acid Proteinase Secreted by Candida Tropicalis: Functional Analysis of Preproregion Cleavages in C. Tropicalis and Saccharomyces Cerevisiae [PDF]

open access: yesMicrobiology, 1996
The 40 kDa secreted aspartyl proteinase (Sapt1) of Candida tropicalis is a pepsin-like enzyme encoded by the SAPT1 gene. According to the deduced amino acid sequence, Sapt1 has a putative preproregion of 60 amino acids preceding the mature enzyme. Maturation and processing of Sapt1 was analysed in C.
Giuseppe, Togni   +4 more
openaire   +2 more sources

Similarities and Differences among Species Closely Related to Candida albicans: C. tropicalis, C. dubliniensis, and C. auris

open access: yesCellular Microbiology, 2022
Although Candida species are widespread commensals of the microflora of healthy individuals, they are also among the most important human fungal pathogens that under certain conditions can cause diseases (candidiases) of varying severity ranging from mild superficial infections of the mucous membranes to life-threatening systemic infections.
Dorota Satala   +7 more
openaire   +3 more sources

Azole non-susceptible C. tropicalis and polyclonal spread of C. albicans in Central Vietnam hospitals

open access: yesThe Journal of Infection in Developing Countries, 2023
Introduction: Candida spp. are responsible for infections ranging from local to systemic, and resistance to antifungal first-line therapy is increasing in non-albicans Candida species. We aimed to determine the etiology of candidiasis and the antifungal resistance of Candida spp. isolated in Hue hospitals, Central-Vietnam.
Thi Minh Chau Ngo   +6 more
openaire   +4 more sources

Comparison of Secretory Acid Proteinases fromCandida tropicalis, C. parapsilosisandC. albicans [PDF]

open access: yesMicrobiology and Immunology, 1992
AbstractAcid proteinases secreted byCandida tropicalisandC. parapsilosiswere newly isolated. Their physico‐chemical and enzymatic properties of molecular weight, pH stability, isoelectric points, specific activity, and N‐terminal amino acid sequences were determined and compared with those of aC. albicansacid proteinase.
E, Sono   +6 more
openaire   +2 more sources

Copper and silver doped in CdTe quantum dots: C. albicans and C. tropicalis antifungal nanomaterials

open access: yesMaterials Research Express, 2023
Abstract Quantum dots based on CdTe and Copper or Silver doped CdTe were used for antifungal against C. albicans and C. tropicalis by microdilution method protocol by CLSI. Pure and doped QDs were characterized by UV–vis and fluorescence spectroscopy, x-ray diffraction and transmission electron microscopy which showed sizes between 7.1 ...
Antonio Tirado-Guizar   +3 more
openaire   +2 more sources

NADPH‐Cytochrome c Reductase of Candida tropicalis Grown on Alkane [PDF]

open access: yesEuropean Journal of Biochemistry, 1979
During growth on n‐tetradecane Candida tropicalis synthesizes a NADPH‐cytochrome c reductase whose level is 4‐times higher than that of cells grown on glycerol and 20‐times higher than that of cells grown on glucose. An original method of solubilisation of this enzyme based on an osmotic shock is described. Studies of the purified enzyme showed that it
J C, Bertrand   +4 more
openaire   +2 more sources

Effect of Piper betle and Brucea javanica on the Differential Expression of Hyphal Wall Protein (HWP1) in Non-Candida albicans Candida (NCAC) Species [PDF]

open access: yes, 2014
The study aimed to identify the HWP1 gene in non-Candida albicans Candida species and the differential expression of HWP1 following treatment with Piper betle and Brucea javanica aqueous extracts.
Harun, Whaw   +3 more
core   +1 more source

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