Results 31 to 40 of about 56,587 (222)
Inbreeding ratio and genetic relationships among strains of the Western clawed frog, Xenopus tropicalis [PDF]
, 2015 The Western clawed frog, Xenopus tropicalis, is a highly promising model amphibian, especially in developmental and physiological research, and as a tool for understanding disease.
Fujii, Tamotsu +10 more
core +4 more sources
European Journal of Medical Research, 2020 Background Vulvovaginal candidiasis (VVC) represents a universal health hazard that contributes to significant morbidity in women. Resistance of Candida to antifungal therapy has been reported as a public health problem.
Mohamed T. Yassin +3 more
doaj +1 more source
Dependence on Mincle and Dectin-2 Varies With Multiple Candida Species During Systemic Infection
Frontiers in Microbiology, 2021 More than 95% of invasive Candida infections are caused by four Candida spp. (C. albicans, C. glabrata, C. tropicalis, C. parapsilosis). C-type lectin-like receptors (CLRs), such as Dectin-1, Dectin-2, and Mincle mediate immune responses to C.
Aiysha Thompson +12 more
doaj +1 more source
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]
, 2016 Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien +12 more
core +2 more sources
Candida tropicalis distribution and drug resistance is correlated with ERG11 and UPC2 expression
Antimicrobial Resistance and Infection Control, 2021 Background Candida tropicalis (C. tropicalis) is an important opportunistic pathogenic Candida species that can cause nosocomial infection. In this study, we analyzed the distribution and drug susceptibility of C.
Dan Wang +5 more
doaj +1 more source
TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]
, 2015 Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David +8 more
core +3 more sources
Infection and Drug Resistance, 2022 Xianggui Yang,1,* Mingquan Liu,1,* Xuejing Yu,2 Zhenguo Wang,3 Ying Xu1 1Department of Laboratory Medicine, Clinical Medical College and the First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, People’s Republic of China ...
Yang X, Liu M, Yu X, Wang Z, Xu Y
doaj
PLoS Pathogens, 2021 Candida tropicalis is a human pathogen that primarily infects the immunocompromised. Whereas the genome of one isolate, C. tropicalis MYA-3404, was originally sequenced in 2009, there have been no large-scale, multi-isolate studies of the genetic and ...
Caoimhe E O'Brien +8 more
doaj +1 more source
Voriconazole treatment of Candida tropicalis meningitis: persistence of (1,3)-b-D-glucan in the cerebrospinal fluid is a marker of clinical and microbiological failure [PDF]
, 2016 Introduction: Infections are still the most common complications of cerebral shunt procedures. Even though fungal etiologies are considered to be rare, they are associated with significant morbidity and mortality.
Brunetti, Grazia +7 more
core +2 more sources
Experimental Hematology & Oncology, 2022 Background Accumulating evidence implicates that gut fungi are associated with the pathogenesis of colorectal cancer (CRC). Our previous study has revealed that Candida tropicalis (C.
Zhiyong Zhang +9 more
doaj +1 more source