Results 61 to 70 of about 56,587 (222)

Breakthrough Bloodstream Infections Caused by Echinocandin-Resistant Candida tropicalis: An Emerging Threat to Immunocompromised Patients with Hematological Malignancies

Journal of Fungi, 2020
Background. Candida tropicalis is a virulent fungal pathogen for which echinocandins are the primary therapy. Emergence of resistance to echinocandins of C. tropicalis carries potentially ominous therapeutic implications. Methods.
Maroun M. Sfeir, Cristina Jiménez-Ortigosa, Maria N. Gamaletsou, Audrey N. Schuetz, Rosemary Soave, Koen Van Besien, Catherine B. Small, David S. Perlin, Thomas J. Walsh   +8 more
doaj   +1 more source

A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus [PDF]

, 2019
During vertebrate embryogenesis, the cranial neural crest (CNC) forms at the neural plate border and subsequently migrates and differentiates into many types of cells.
Duncan, Melinda K., Li, Jiejing, Li, Rebecca, Materna, Christopher, Perfetto, Mark, Tran Thi, Hong, Vleminckx, Kris, Wei, Shuo   +7 more
core   +1 more source

Patterns of spinal motion, kinematic spaces and the land‐to‐sea transition in carnivorans

The Anatomical Record, EarlyView.
Using 3D reconstructions, we quantify intervertebral joint mobility to investigate how cervical, thoracic, and lumbar vertebral regions evolved distinct kinematic roles in pinnipeds. The findings reveal lineage‐specific adaptations for swimming and highlight the functional significance of vertebral joint flexibility in ecological transitions.
Juan Miguel Esteban, Alberto Martín‐Serra, Alejandro Pérez‐Ramos, Borja Figueirido   +3 more
wiley   +1 more source

Candida Isolates From Blood and Other Normally Sterile Foci From ICU Patients: Determination of Epidemiology, Antifungal Susceptibility Profile and Evaluation of Associated Risk Factors

Frontiers in Public Health, 2021
Background: The clinical diagnosis and therapy for ICU patients with invasive candidiasis are challenged by the changes of Candida community composition and antimicrobial resistance.
Bo Wang, Xinlong He, Xinlong He, Feng Lu, Feng Lu, Yajuan Li, Yuerong Wang, Min Zhang, Ying Huang, Jinxing Xia   +9 more
doaj   +1 more source

Insights into Candida tropicalis virulence factors [PDF]

, 2011
Candida tropicalis is a common nosocomial species related to candidemia and candiduria. Several virulence factors seem to be responsible for C. tropicalis infections, which lead to high mortality.
Azeredo, Joana, Henriques, Mariana, Negri, M., Oliveira, Rosário, Silva, Sónia Carina, Svidzinski, T.   +5 more
core  

Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]

, 2013
Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Ballus, Jose, Bingold, Tobias Michael, Kaskel, Peter, Krobot, Karl J., Kumar, Ritesh N., Mavros, Panagiotis, Nocea, Gonzalo, Wissing, Heimo   +7 more
core   +1 more source

Whole tissue imaging of cellular boundaries at sub‐micron resolutions for deep learning cell segmentation: Applications in the analysis of epithelial bending of ectoderm

Developmental Dynamics, EarlyView.
Abstract Background To understand cellular morphology, biologists have relied on traditional optical microscopy of tissues combined with tissue clearing protocols to image structures deep within tissues. Unfortunately, these protocols often struggle to retain cell boundary markers, especially at high enough resolutions necessary for precise cell ...
Sam C. P. Norris, Jimmy K. Hu, Neil H. Shubin   +2 more
wiley   +1 more source

Emergence of Flucytosine-Resistant Candida tropicalis Clade, the Netherlands

Emerging Infectious Diseases
Candida tropicalis is the second most virulent Candida species after C. albicans. Previous studies from the Netherlands and France reported a notable reduction in susceptibility to flucytosine (5-FC) in a substantial proportion of C. tropicalis isolates.
Fatima Zohra Delma, Bram Spruijtenburg, Jacques F. Meis, Auke W. de Jong, James Groot, Johanna Rhodes, Willem J.G. Melchers, Paul E. Verweij, Theun de Groot, Eelco F.J. Meijer, Jochem B. Buil   +10 more
doaj   +1 more source

Candida tropicalis biofilms : formation and virulence factors [PDF]

, 2010
Significance and objectives: A substantial proportion of Candida tropicalis infections is associated with biofilm formation, especially on catheters. Thus, the aim of this study was to investigate C.
Botelho, C. M., Henriques, Mariana, Negri, M., Oliveira, Rosário, Silva, Sónia Carina, Svidzinski, T.   +5 more
core  

What are the vector species of the Oropouche virus?

Pest Management Science, EarlyView.
Here, we review the timeline of Oropouche virus (OROV) detection in various hematophagous Diptera, from 1955 to date, including mosquitoes and midges. All vector competence experiments also are described. The results suggest that Culicoides are the primary vectors.
Constância Flávia Junqueira Ayres, Bruna Lais Sena do Nascimento, Daniele Barbosa de Almeida Medeiros, Joaquim Pinto Nunes Neto   +3 more
wiley   +1 more source