Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen +14 more
wiley +1 more source
Hypersensitivity reactions amongst Hungarian Patients with Hereditary Angioedema due to C1-Inhibitor Deficiency. [PDF]
Horváth HR +5 more
europepmc +1 more source
Hormonális változások hatása a C1-inhibitor deficiencia következtében kialakuló herediter angioödémás betegek klinikai tüneteire [PDF]
Czaller, Ibolya
core +1 more source
Administration of C1 Inhibitor Reduces Neutrophil Activation in Patients with Sepsis
Sacha Zeerleder +6 more
openalex +1 more source
Pre-procedure Administration of C1 Esterase Inhibitor (Human) (Cinryze™) for the Prevention of Hereditary Angioedema (HAE) Attacks after Medical, Dental, or Surgical Procedures [PDF]
William R. Lumry +7 more
openalex +1 more source
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu +23 more
wiley +1 more source
Inhibiting plasma kallikrein for hereditary angioedema prophylaxis [PDF]
et al,, Wedner, H. J.
core +2 more sources
We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard +8 more
wiley +1 more source
Citrullination of C1-inhibitor as a mechanism of impaired complement regulation in rheumatoid arthritis. [PDF]
Martin M +12 more
europepmc +1 more source
Human oligodendroglial cells express low levels of C1 inhibitor and membrane cofactor protein mRNAs. [PDF]
Masato Hosokawa +2 more
openalex +1 more source

