Results 231 to 240 of about 595,845 (281)

Retrospective analysis of the transmission of difficult-to-treat resistant Pseudomonas aeruginosa - genotype beats phenotype. [PDF]

Antimicrob Resist Infect Control
Jasuja JK, Maurer PM, Carlsen L, Klupp ET, Belmar Campos CE, Rohde H, Aepfelbacher M, Knobloch JK.   +7 more
europepmc   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Structural Centrality Versus Inferred Ancestral State: Unraveling Hidden Heterogeneity in Large HIV Molecular Clusters. [PDF]

Viruses
Lai L, Luo Y, Li S, Song Y, Wu H, Cai Y, Tian Z, Yi Y, Yao Z, Yan H, Han Z, Liu Y.   +11 more
europepmc   +1 more source

Spatial Au+ Mapping Reveals a Self‐Amplifying Anti‐Tumor Immunity Loop Driven by Au(I) Complexes

Advanced Science, EarlyView.
The first report of spatial Au+ mapping of a representative gold complex (Au9). Macrophages, DCs, and tumor cells ranked as the top three in Au+ enrichment after Au9 treatment. Interestingly, Au9 treatment could induce ferroptosis and suppress cellular cholesterol, further eliciting a self‐amplifying anti‐tumor immunity loop.
Zhongren Xu, Zhiyue Fan, Lin Lv, Wei Lu, Zhenfan Wen, Wukun Liu   +5 more
wiley   +1 more source

Beyond Swelling: Clinical Insights into the Diagnosis and Management of Hereditary Angioedema. [PDF]

Int J Mol Sci
Paulauskiene M, Tamasauskiene L, Gradauskiene B.   +2 more
europepmc   +1 more source

Clonotypic characterization defines B-cell drivers of clonal expansion and intratumor heterogeneity in IgM monoclonal gammopathies. [PDF]

Hemasphere
Moreno DF, Nadeu F, Casado-Peláez M, Mata C, Márquez-López I, Fernández MA, Vaqué S, Medina E, Llobregat H, Garrote M, Mañé J, Cardús O, Rodríguez-Lobato LG, de Daniel A, Cibeira MT, Gremen Oliveira T, Kulaeva E, Lozano E, Colomer D, Rosiñol L, van Boxtel R, Esteller M, Fernández de Larrea C.   +22 more
europepmc   +1 more source

Effect of Feedstock Composition on Physicochemical and Microbiological Properties of Compost from Tuber and Acidic Fruit Peel Residues. [PDF]

ACS Omega
Bernal Peña LN, Bohorquez F, Hernandez E, Morales AN, Caicedo W, Rueda Cadavid DA.   +5 more
europepmc   +1 more source

The perceptual geometry and chromaticity of near-death experience spaces. [PDF]

Front Psychol
Lerner F, Dos Santos PCR, Tahar G.
europepmc   +1 more source