Results 191 to 200 of about 571,919 (313)

1-Ethenyl-2-(methyl-sulfan-yl)-4,4-diphenyl-4,5-di-hydro-1<i>H</i>-imidazol-5-one (Thio-phenytoin analogue): synthesis, structure and Hirshfeld surface analysis. [PDF]

Acta Crystallogr E Crystallogr Commun
El Moutaouakil Ala Allah A, Massera C, Mague JT, Alsubari A, Ramli Y.   +4 more
europepmc   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Prop-2-enyl 6-amino-5-cyano-4-(4-iso-propylphen-yl)-2-methyl-4<i>H</i>-pyran-3-carboxyl-ate. [PDF]

IUCrdata
Kumar CU, Krishnan GA, Rani PJ, Pillai MV, Mohandas T.   +4 more
europepmc   +1 more source

Konzert (GS C18)

, 2021
openaire   +1 more source

The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

Advanced Science, EarlyView.
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang, Zijin Liu, Minshan Jin, Junting Liu, Shihao Wei, Dengmao Yang, Saiqi Yang, Yuan Guo, Mingxun Chen   +8 more
wiley   +1 more source

A second monoclinic polymorph of ferrocenecarboxaldehyde. [PDF]

Acta Crystallogr E Crystallogr Commun
Lasri J, Almehmadi YA, Eltayeb NE, Hökelek T, McKay AP.   +4 more
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Transcriptome-based analysis of oil accumulation pattern and key gene screening in <i>Gardenia jasminoides</i> fruits. [PDF]

Front Plant Sci
Su L, Cao J, Chen Y, Li P, Chen J, Li C, Liu Q, Xiao Z, Cao H, Kuang D, Wu A, Lu Y, Zhou X, Yang Y.   +13 more
europepmc   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

3-Hydroxystearic acid promotes cholesterol efflux and attenuates atherosclerosis via the ALKBH5/PAX-8/ABCA1 pathway. [PDF]

Front Immunol
Zhou QY, Liu W, Zhao ZW, Gong D, Ma XF, Tang CK.   +5 more
europepmc   +1 more source