Results 171 to 180 of about 119,425 (295)

Dislocation‐Mediated Lattice Distortion and Griffiths Phase Behavior in Melt‐Spun Ni2MnSb Ribbons

open access: yesAdvanced Science, EarlyView.
This figure illustrates how melt‐spinning introduces dislocations into Ni2MnSb Heusler alloys. TEM images reveal local lattice distortions and associated strain fields surrounding dislocations at a representative wheel speed. As wheel speed increases, these distortions promote the formation of ferromagnetic clusters within a paramagnetic matrix ...
Kun Wang   +11 more
wiley   +1 more source

Population-scale analysis reveals inherited C1-inhibitor deficiency is a polyphenotypic thrombotic disorder. [PDF]

open access: yesBlood Adv
Rodriguez Espada A   +15 more
europepmc   +1 more source

Citrullination of C1-inhibitor as a mechanism of impaired complement regulation in rheumatoid arthritis. [PDF]

open access: yesFront Immunol, 2023
Martin M   +12 more
europepmc   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

Angioedema due to acquired C1 inhibitor deficiency: patient experience, conceptual disease model, and assessment of patient-reported outcome measures. [PDF]

open access: yesFront Immunol
de Lange M   +10 more
europepmc   +1 more source

Beyond Electrostatics: Anion‐π+ Orbital Hybridization Underpins High‐Performance Chloride Storage in Poly(arylamine) Organic Cathodes

open access: yesAdvanced Science, EarlyView.
The fundamental nature of anion storage in p‐type organic cathodes is elucidated using rigid poly(arylamine) frameworks. This study reveals a hybrid covalent‐ionic mechanism for anion‐π+ interactions, driven by synergistic orbital hybridization and electrostatic attraction.
Tiantian She   +7 more
wiley   +1 more source

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

open access: yesAdvanced Science, EarlyView.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang   +19 more
wiley   +1 more source

Berotralstat effectiveness and safety in patients with hereditary angioedema with normal C1 inhibitor. [PDF]

open access: yesJ Allergy Clin Immunol Glob
Buckland MS   +3 more
europepmc   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu   +20 more
wiley   +1 more source

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