Results 171 to 180 of about 214,320 (304)

A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun, Jing Zhang, Chenqing Liu, Jing Lou, Sihui Wang, Xiangtian Ji, Xiaofang Zhao, Shirui Xu, Jingyu Feng, Bin Liu, Chao Chang, Qinggang Ge, Jun Yang   +12 more
wiley   +1 more source

Population-scale analysis reveals inherited C1-inhibitor deficiency is a polyphenotypic thrombotic disorder. [PDF]

Blood Adv
Rodriguez Espada A, Haj AK, Jurgens SJ, Eswaran H, Sundler Björkman L, Ryu J, Chaudhry S, Koyama S, Wang X, Choi SH, Sanna-Cherchi S, Banerji A, Rämö JT, Ellinor PT, Grover SP, Bendapudi PK.   +15 more
europepmc   +1 more source

C1 inhibitor deficiency enhances contact pathway-mediated activation of coagulation and venous thrombosis. [PDF]

Blood, 2023
Grover SP, Kawano T, Wan J, Tanratana P, Polai Z, Shim YJ, Snir O, Brækkan S, Dhrolia S, Kasthuri RR, Bendapudi PK, Bendapudi PK, McCrae KR, Wolberg AS, Hansen JB, Farkas H, Mackman N.   +16 more
europepmc   +1 more source

High‐Performance Prevascularized SHED‐Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair

Advanced Science, EarlyView.
A high‐performance 3D scaffold integrating rGO and SHEDs is developed to overcome impaired healing in diabetic bone defects. By driving extracellular matrix remodeling, rGO creates a pro‐angiogenic niche that significantly accelerates in vitro vascular network formation.
Can Zhang, Yiyuan Kang, Shulin Lai, Chunyi Wang, Guixin He, Kehui Jian, Suhan Yin, Xiner Tan, Xinru Zhou, Wenjing Liu, Fujian Zhao, Jia Liu, Longquan Shao   +12 more
wiley   +1 more source

Berotralstat effectiveness and safety in patients with hereditary angioedema with normal C1 inhibitor. [PDF]

J Allergy Clin Immunol Glob
Buckland MS, Boccon-Gibod I, De Moreuil C, Sanges S.   +3 more
europepmc   +1 more source

Phase‐Resolved Defect Transport Mechanisms Governing Asynchronous Ordering in a Eutectic High‐Entropy Alloy

Advanced Science, EarlyView.
Phase‐resolved experiments and atomistic simulations reveal asynchronous ordering behaviors in a eutectic high‐entropy alloy during isothermal annealing. Distinct defect transport mechanisms are identified in coexisting B2 and BCC phases, showing that vacancy and interstitial mediated diffusion governs phase‐dependent thermal stability.
Huiwen Yao, Qingshuang Ma, Jie Xiong, Jing Bai, Huijun Li, Qiuzhi Gao   +5 more
wiley   +1 more source

Health-related quality of life in hereditary angioedema patients treated with subcutaneous C1 inhibitor (C1-INH) therapy in Canada. [PDF]

Allergy Asthma Clin Immunol
Waserman S, Lacuesta G, Kanani AS, Sussman GL, Kim H, Chapdelaine H, Goubran Messiha HA, Kalicinsky C, Adatia A, Yap B, Dansereau MF, Tanios N, El-Sayegh R, Martin A, Mahfouz H, Machnouk M, Keith PK.   +16 more
europepmc   +1 more source

A Retrospective Analysis of Long-Term Prophylaxis with Berotralstat in Patients with Hereditary Angioedema and Acquired C1-Inhibitor Deficiency-Real-World Data. [PDF]

Clin Rev Allergy Immunol, 2023
Johnson F, Stenzl A, Hofauer B, Heppt H, Ebert EV, Wollenberg B, Lochbaum R, Hahn J, Greve J, Trainotti S.   +9 more
europepmc   +1 more source

CsPbBr3–Nanodiamonds Hybrid Wafers for Mechanically Robust, High‐Performance X‐Ray Detection

Advanced Electronic Materials, EarlyView.
NDs‐engineered CsPbBr3 hybrid wafers, fabricated via scalable solid‐state grinding and cold pressing, utilize trace NDs to regulate mechanochemical conversion, promote heterogeneous nucleation, bridge grain boundaries, and passivate interfacial defects. The optimized wafer exhibits dense microstructures, improved charge transport, reduced dark current,
Yanan Gong, Zhuangjie Xu, Weidong Zhu, Xiaoxuan Zhang, Zihao Wang, Zeyang Ren, Yanshuang Ba, He Xi, Zhimin Li, Chunfu Zhang, Jincheng Zhang, Yue Hao   +11 more
wiley   +1 more source

Clinical validity of dried blood spot assay for the measurement of functional C1 inhibitor in angioedema due to C1 inhibitor deficiency. [PDF]

J Allergy Clin Immunol Glob
Bernstein JA, Cheng J, Pisani T, Sexton D, Whitaker RE, Nova Estepan D, Inhaber N.   +6 more
europepmc   +1 more source