Results 251 to 260 of about 62,354 (276)

Platelet C1q receptor interactions with collagen- and C1q-coated surfaces.

The Journal of Immunology, 1990
Abstract We recently described specific binding sites for C1q on human blood platelets. Structural similarities between the amino-terminal of C1q and collagen have suggested that receptors for both molecules on platelets might be the same.
E I, Peerschke, B, Ghebrehiwet
openaire   +2 more sources

Ultrastructure of Human C1q Protein

Nature New Biology, 1972
THE first component (C1) in the complement system may be defined functionally as a macromolecule capable of binding to antigen-antibody complexes and inducing the sequential reactions of this system. C1 consists of three distinct proteins named C1q, C1r and C1s which,in serum, form a macromolecular complex held together by calcium ions1.
S E, Svehag, L, Manhem, B, Bloth
openaire   +2 more sources

A method to differentiate between anti-C1q antibodies and C1q-binding immune complexes using collagenase-digested solid phase C1q

Journal of Immunological Methods, 1991
A method for the detection of circulating immune complexes in the presence of autoantibodies to C1q is described. Solid phase C1q-digestion with bacterial collagenase results in the elimination of the collagen-like region of C1q. Binding of model immune complexes to this modified solid phase C1q is practically unaltered, while reactivity of anti-C1q ...
J E, Menzel, O, Scherak, G, Kolarz, F, Gamerith, U, Youngchaiyud   +4 more
openaire   +2 more sources

C1q

Nihon rinsho. Japanese journal of clinical medicine, 2000
Franz Petry, Michael Loos
openaire   +3 more sources

C1q levels in hereditary angioedema

Journal of Allergy and Clinical Immunology, 1977
In 21 affected members from 4 kindreds with hereditary angioedema, serum C1q levels generally were in the lower part of the normal range, with some values clearly below the lower limit of normal. The serum C1q levels in patients with hereditary angioedema were significantly depressed when compared with those in unaffected family members (p less than 0 ...
openaire   +2 more sources

Classical Complement Pathway Component C1q: Purification of Human C1q, Isolation of C1q Collagen-Like and Globular Head Fragments and Production of Recombinant C1q—Derivatives. Functional Characterization

2013
The classical complement pathway (CCP) activation is a multimolecular complex, composed of three subcomponents namely C1q, C1r, and C1s. C1q is the recognition subunit of this complex and its binding to the specific targets leads to the formation of active C1, which in turn activates the CCP in an immunoglobulin-dependent or -independent manner. C1q is
openaire   +2 more sources

C1q receptor

1987
openaire   +2 more sources

C1q Nephropathy

American Journal of Kidney Diseases, 1999
openaire   +1 more source

C1q

2018
openaire   +1 more source

AUTOANTIBODIES TO C1q

2007
openaire   +1 more source