Results 51 to 60 of about 619,403 (240)

The demographic, clinical, and management differences between traumatic dens fracture patients with and without simultaneous atlas fractures

Journal of Craniovertebral Junction and Spine
Introduction: Atlas fractures often accompany traumatic dens fractures, but existing literature on the management of simultaneous atlantoaxial fractures is limited.
Michael Brendan Cloney, Pavlos Texakalidis, Anastasios G Roumeliotis, Vineeth Thirunavu, Nathan A Shlobin, Kevin Swong, Najib El Tecle, Nader S Dahdaleh   +7 more
doaj   +1 more source

Muraymycin nucleoside-peptide antibiotics: uridine-derived natural products as lead structures for the development of novel antibacterial agents

Beilstein Journal of Organic Chemistry, 2016
Muraymycins are a promising class of antimicrobial natural products. These uridine-derived nucleoside-peptide antibiotics inhibit the bacterial membrane protein translocase I (MraY), a key enzyme in the intracellular part of peptidoglycan biosynthesis ...
Daniel Wiegmann, Stefan Koppermann, Marius Wirth, Giuliana Niro, Kristin Leyerer, Christian Ducho   +5 more
doaj   +1 more source

Enhanced Stability of DNA Oligonucleotides with Partially Zwitterionic Backbone Structures in Biological Media

Molecules, 2018
Deficient stability towards nuclease-mediated degradation is one of the most relevant tasks in the development of oligonucleotide-derived biomedical agents.
Melissa Meng, Boris Schmidtgall, Christian Ducho   +2 more
doaj   +1 more source

B16-luc, LLC1-luc, TRAMP-C2-luc and microsphere dissemination (7 and 16 μm diameter) in soft tissues.

, 2016
(A) Individual lung dissemination of tumor cells varied between ~30–40%. In contrast, very few microbeads (independent of their size) were found in the lung. All cell types disseminated significantly higher to the lung compared to microbeads (B16-luc vs.
Christian J. Hoffmann (3107976), Peter Vajkoczy (138176), Thomas Broggini (3107982), Christoph Harms (584894), Andras Piffko (3107985), Marcus Czabanka (3107979)   +5 more
core   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Multinational Mission Command: From Paper to Practice in NATO

Scandinavian Journal of Military Studies
With the 2022 update to NATO’s AJP-01 Allied Joint Doctrine, mission command was elevated from an important component of a joint command philosophy to the alliance’s overarching command philosophy – a shift in written doctrine raising concerns about its ...
Søren Sjøgren, Niklas Nilsson
doaj   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Advantages of the point-intercept method for assessing functional diversity in semi-arid areas

iForest - Biogeosciences and Forestry, 2015
Semi-arid areas are particularly susceptible to the loss of biodiversity as a consequence of global change. Species functional traits are key drivers of functioning and resilience of ecosystems, thus monitoring of functional trait diversity is urgently ...
Nunes A, Tápia S, Pinho P, Correia O, Branquinho C   +4 more
doaj   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Public Health Expenditure and Maternal Mortality Rate in Sub-Saharan African Countries

Studia Universitatis Vasile Goldis Arad, Seria Stiinte Economice
The study looked at public health spending and maternal mortality in Sub-Saharan Africa (SSA). The specific objectives were to: investigate the impact of public health expenditure on maternal mortality in Sub-Saharan Africa; determine whether there is a ...
Eze Afamefuna A., Usman Philip F., Ukwueze Ezebuilo R.   +2 more
doaj   +1 more source