Results 171 to 180 of about 4,044,136 (204)
Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. [PDF]
Cell Death Differ, 2018 Brennan AJ +11 more
europepmc +1 more source
SOME RESULTS ON COUSIN-I DOMAINS OVER C2
Memoirs of the Faculty of Science, Kyushu University. Series A, Mathematics, 1960 openaire +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Otoferlin: a multi-C2 domain protein essential for hearing.
Trends in Neurosciences, 2012Sound is encoded at synapses between cochlear inner hair cells and the auditory nerve. These synapses are anatomically and functionally specialized to transmit acoustic information with high fidelity over a lifetime. The molecular mechanisms of hair-cell transmitter release have recently attracted substantial interest.
T. Pangršič, E. Reisinger, T. Moser
semanticscholar +3 more sources
Functional mapping of factor VIII C2 domain
Thrombosis and Haemostasis, 2011SummaryThe factor VIII (FVIII) is a cofactor of the coagulation cascade. The FVIII C2 domain is a critical domain that participates in the interactions with the von Willebrand factor and the phospholipidic surfaces. To assess the importance of each residue of this domain in the maintenance of the structure and the function of FVIII, a number (n=139) of
Pellequer, Jean-Luc +5 more
openaire +2 more sources
C2 Domains and Membrane Fusion
2011Publisher Summary This chapter describes C2 domains and membrane fusion. Membrane fusion or the controlled merger of two initially separated membranes is of fundamental importance in biology. This is particularly true for eukaryotic cells that contain a plethora of membrane-bound compartments.
Martens, Sascha, McMahon, Harvey T
openaire +2 more sources
Membrane binding and subcellular targeting of C2 domains
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2006C2 domains are a ubiquitous structural module and many of them function in Ca2+ -dependent membrane binding and thereby serve as Ca2+ effectors for divergent Ca2+ -mediated cellular processes. Extensive structural, biochemical, biophysical, and cellular studies of C2 domains and host proteins in the past decade have shown that due to their structural ...
Wonhwa, Cho, Robert V, Stahelin
openaire +2 more sources
Science Signaling, 2001
The originally described C2 domains function as calcium-regulated phospholipid-binding domains. Several examples of proteins that have C2 domains (as identified by sequence similarity) have been found, yet these C2 domains have mutations in key residues that are required for calcium binding.
openaire +2 more sources
The originally described C2 domains function as calcium-regulated phospholipid-binding domains. Several examples of proteins that have C2 domains (as identified by sequence similarity) have been found, yet these C2 domains have mutations in key residues that are required for calcium binding.
openaire +2 more sources
Crystal structure of human Intersectin-2L C2 domain
Biochemical and Biophysical Research Communications, 2013Intersectin-2L (ITSN-2L) is a long isoform of ITSN family, which is a multimodule scaffolding protein functioning in membrane-associated molecular trafficking and signal transduction pathways. ITSN-2L possesses a carboxy-terminal extension encoding a Dbl homology domain (DH), a pleckstrin homology domain (PH) and a C2 domain, suggesting that it could ...
Wei, Zhang +7 more
openaire +2 more sources