Results 151 to 160 of about 157,920 (289)

Framework for C2 Concept Development : Exploring Design Logic and Systems Engineering

open access: yes, 2018
The conditions for military operations have changed due to, e.g., globalization, climate change, and nations' ambitions and actions. This has resulted in new demands on command and control (C2) capability.
Hallberg, Niklas   +3 more
core  

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

Gene synthesis, cloning, expression, purification and biophysical characterization of the C2 domain of human tensin

open access: yes, 2007
Tensin is a large docking protein found in the adhesive junctions of animal cells and recruited early in the development of cell-substrate contacts. There it binds to the cytoplasmic domain of integrin β1 and caps the barbed ends of filamentous actin ...
Gajula, Kiran Sukumar
core  

RAGE-C2 domain interacts with the PA loop #103.

open access: yes, 2013
A. Overlay of 1H{15N}-HSQC spectra of free (black) and PA #103-bound (red) [U- 15N] RAGE-C2 domain. B. Overlay of 1H{15N}-HSQC spectra of free (black) and RAGE-C2 domain-bound (red) [U- 15N] PA #103.
Jing Xue (170229)   +5 more
core   +1 more source

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

open access: yesAdvanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang   +18 more
wiley   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

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