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Hyaluronic acid–lipid binding [PDF]

open access: yesBMC Chemistry, 2021
Background Phospholipid (PL)–hyaluronic acid (HA) interactions are relevant to aging-associated vitreous humor liquefaction, therapies for dry eye disease, skin-care products and synovial joint lubrication.
Anthony Ewurum   +4 more
doaj   +5 more sources

Features and Possible Applications of Plant Lipid-Binding and Transfer Proteins [PDF]

open access: yesMembranes, 2022
In plants, lipid trafficking within and inside the cell is carried out by lipid-binding and transfer proteins. Ligands for these proteins are building and signaling lipid molecules, secondary metabolites with different biological activities due to which ...
Daria N. Melnikova   +4 more
doaj   +2 more sources

Lipid Binding Proteins from Parasitic Platyhelmithes [PDF]

open access: yesFrontiers in Physiology, 2012
Two main families of lipid binding proteins have been identified in parasitic Platyhelminthes: hydrophobic ligand binding proteins (HLBPs) and fatty acid binding proteins (FABPs). Members of the former family of proteins are specific to the Cestoda class,
Gabriela eAlvite, Adriana eEsteves
doaj   +3 more sources

Lipid binding domains: more than simple lipid effectors

open access: yesJournal of Lipid Research, 2009
The spatial and temporal regulation of lipid molecules in cell membranes is a hallmark of cellular signaling and membrane trafficking events. Lipid-mediated targeting provides for strict control and versatility, because cell membranes harbor a large ...
Robert V. Stahelin
doaj   +3 more sources

PTEN-lipid Binding Assay

open access: yesBio-Protocol, 2013
The lipid and protein interactions are an integral and important part of many cellular signaling pathways. The understanding of the selective and specific interaction of the given lipid molecule with the target protein is required for studying cellular ...
Sridhar Kavela   +2 more
doaj   +2 more sources

Structure and Membrane Targeting of the PDZD7 Harmonin Homology Domain (HHD) Associated With Hearing Loss

open access: yesFrontiers in Cell and Developmental Biology, 2021
Usher syndrome (USH) is the leading cause of hereditary hearing–vision loss in humans. PDZ domain-containing 7 (PDZD7) has been reported to be a modifier of and contributor to USH.
Lin Lin   +6 more
doaj   +1 more source

Identification and Characterization Analysis of Transient Receptor Potential Mucolipin Protein of Laodelphax striatellus Fallén

open access: yesInsects, 2021
Transient receptor potential mucolipin (TRPML) protein in flies plays a pivotal role in Ca2+ ions release, resulting in membrane trafficking, autophagy and ion homeostasis.
Haitao Wang   +4 more
doaj   +1 more source

Do Lipids Influence Gastrointestinal Processing: A Case Study of Major Soybean Allergen Gly m 4

open access: yesMembranes, 2021
Previously, we have demonstrated that Gly m 4, one of the major soybean allergens, could pass through the Caco-2 epithelial barrier and have proposed a mechanism of sensitization.
Ekaterina I. Finkina   +4 more
doaj   +1 more source

μ-calpain binds to lipid bilayers via the exposed hydrophobic surface of its Ca2+-activated conformation [PDF]

open access: yes, 2006
μ- and m-calpain are cysteine proteases requiring micro- and millimolar Ca2+ concentrations for their activation in vitro. Among other mechanisms, interaction of calpains with membrane phospholipids has been proposed to facilitate their activation by ...
Fernández-Montalván, Amaury   +5 more
core   +4 more sources

Cholesterol metabolism is altered in Rett syndrome: A study on plasma and primary cultured fibroblasts derived from patients [PDF]

open access: yes, 2014
Rett (RTT) syndrome is a severe neurological disorder that affects almost exclusively females. Several detectable mutations in the X-linked methyl-CpG-binding protein 2 gene (MECP2) are responsible for the onset of the disease.
Di Tunno, Ilenia   +6 more
core   +13 more sources

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