Results 41 to 50 of about 1,084,218 (302)

The molecular basis of ceramide-1-phosphate recognition by C2 domains[S]

open access: yesJournal of Lipid Research, 2013
Group IVA cytosolic phospholipase A2 (cPLA2α), which harbors an N-terminal lipid binding C2 domain and a C-terminal lipase domain, produces arachidonic acid from the sn-2 position of zwitterionic lipids such as phosphatidylcholine. The C2 domain has been
Katherine E. Ward   +5 more
doaj   +1 more source

Lipid membrane binding of NK‐lysin

open access: yesFEBS Letters, 1998
The membrane‐binding properties and pore‐forming potential of the tumor‐lysing and antibacterial polypeptide NK‐lysin were investigated. Fluorescence quenching experiments show a drastic change of accessibility to Trp58 in solution and in association with a lipid membrane.
Ruysschaert, Jean Marie   +5 more
openaire   +2 more sources

Naturally occurring variant of mouse apolipoprotein A-I alters the lipid and HDL association properties of the protein

open access: yesJournal of Lipid Research, 2012
Plasma HDL levels are inversely associated with atherosclerosis. Inbred mouse strains differ in plasma HDL levels and susceptibility to atherosclerosis. Atherosclerosis-susceptible C57BL/6J mice possess plasma HDL levels 2-fold lower than atherosclerosis-
Timothy J. Sontag   +4 more
doaj   +1 more source

Effect of Point Mutations on Structural and Allergenic Properties of the Lentil Allergen Len c 3

open access: yesMembranes, 2021
Plant lipid transfer proteins (LTPs) are known to be clinically significant allergens capable of binding various lipid ligands. Recent data showed that lipid ligands affected the allergenic properties of plant LTPs.
Daria N. Melnikova   +6 more
doaj   +1 more source

A saposin-lipoprotein nanoparticle system for membrane proteins. [PDF]

open access: yes, 2016
A limiting factor in membrane protein research is the ability to solubilize and stabilize such proteins. Detergents are used most often for solubilizing membrane proteins, but they are associated with protein instability and poor compatibility with ...
Armache, Jean-Paul   +13 more
core   +2 more sources

Membrane and Protein Interactions of the Pleckstrin Homology Domain Superfamily

open access: yesMembranes, 2015
The human genome encodes about 285 proteins that contain at least one annotated pleckstrin homology (PH) domain. As the first phosphoinositide binding module domain to be discovered, the PH domain recruits diverse protein architectures to cellular ...
Marc Lenoir   +3 more
doaj   +1 more source

Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]

open access: yes, 2014
Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO   +7 more
core   +2 more sources

Insulin-induced lipid binding to hemoglobin [PDF]

open access: yesJournal of the Serbian Chemical Society, 2003
Under hypoglycemic conditions, concomitant hyperinsulinism causes an apparent modification of hemoglobin (Hb) which is manifested by its aggregation (Niketi} et al., Clin. Chim. Acta 197 (1991) 47).
VESNA NIKETIC   +4 more
doaj   +3 more sources

Evidence for the role of proteoglycans in cation-mediated gene transfer [PDF]

open access: yes, 1996
We report evidence that gene complexes, consisting of polycations and plasmid DNA enter cells via binding to membrane-associated proteoglycans. Treatment of HeLa cells with sodium chlorate, a potent inhibitor of proteoglycan sulfation, reduced luciferase
Baldeschwieler, John D.   +1 more
core   +1 more source

Binding of Serotonin to Lipid Membranes [PDF]

open access: yesJournal of the American Chemical Society, 2013
Serotonin (5-hydroxytryptamine, 5-HT) is a prevalent neurotransmitter throughout the animal kingdom. It exerts its effect through the specific binding to the serotonin receptor, but recent research has suggested that neural transmission may also be affected by its nonspecific interactions with the lipid matrix of the synaptic membrane.
Peters, Günther H.J.   +5 more
openaire   +3 more sources

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