Results 41 to 50 of about 2,675,614 (299)
Binding of Peripheral Proteins to Mixed Lipid Membranes: Effect of Lipid Demixing upon Binding [PDF]
Biophysical Journal, 1999 Binding isotherms have been determined for the association of horse heart cytochrome c with dioleoyl phosphatidylglycerol (DOPG)/dioleoyl phosphatidylcholine (DOPC) bilayer membranes over a range of lipid compositions and ionic strengths. In the absence of protein, the DOPG and DOPC lipids mix nearly ideally.
Heimburg, T., Angerstein, B., Marsh, D.
openaire +3 more sources
Effect of Point Mutations on Structural and Allergenic Properties of the Lentil Allergen Len c 3
Membranes, 2021 Plant lipid transfer proteins (LTPs) are known to be clinically significant allergens capable of binding various lipid ligands. Recent data showed that lipid ligands affected the allergenic properties of plant LTPs.
Daria N. Melnikova +6 more
doaj +1 more source
μ-calpain binds to lipid bilayers via the exposed hydrophobic surface of its Ca2+-activated conformation [PDF]
, 2006 μ- and m-calpain are cysteine proteases requiring micro- and millimolar Ca2+ concentrations for their activation in vitro. Among other mechanisms, interaction of calpains with membrane phospholipids has been proposed to facilitate their activation by ...
Machleidt, Werner +5 more
core +1 more source
Journal of Lipid Research, 2005 Apolipoprotein A-IMilano (A-IM) (R173C), a natural mutant of human apolipoprotein A-I (apoA-I), and five other cysteine variants of apoA-I at residues 52 (S52C), 74 (N74C), 107 (K107C), 129 (G129C), and 195 (K195C) were generated.
Xuewei Zhu +4 more
doaj +1 more source
Antimicrobial Peptide-Lipid Binding Interactions and Binding Selectivity [PDF]
Biophysical Journal, 2007 Surface pressure measurements, external reflection-Fourier transform infrared spectroscopy, and neutron reflectivity have been used to investigate the lipid-binding behavior of three antimicrobial peptides: melittin, magainin II, and cecropin P1. As expected, all three cationic peptides were shown to interact more strongly with the anionic lipid, 1,2 ...
Lad, Mitaben D. +5 more
openaire +2 more sources
Lipid metabolism and HCV infection [PDF]
, 2010 Chronic infection by hepatitis C virus (HCV) can lead to severe liver disease and is a global healthcare problem. The liver is highly metabolically active and one of its key functions is to control the balance of lipid throughout the body.
Boulant, Steeve +11 more
core +1 more source
Journal of Lipid Research, 2001 The central region of apolipoprotein A-I (apoA-I), spanning residues 143–165, has been implicated in lecithin:cholesterol acyltransferase (LCAT) activation and also in high density lipoprotein (HDL) structural rearrangements.
Kyung-Hyun Cho +2 more
doaj +1 more source
Insulin-induced lipid binding to hemoglobin [PDF]
Journal of the Serbian Chemical Society, 2003 Under hypoglycemic conditions, concomitant hyperinsulinism causes an apparent modification of hemoglobin (Hb) which is manifested by its aggregation (Niketić et al., Clin. Chim. Acta 197 (1991) 47).
Tomašević Nenad +4 more
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Lipid bilayer composition influences small multidrug transporters [PDF]
, 2008 Background: Membrane proteins are influenced by their surrounding lipids. We investigate the effect of bilayer composition on the membrane transport activity of two members of the small multidrug resistance family; the Escherichia coli transporter, EmrE
Charalambous, K +10 more
core +1 more source
A Soluble Fluorescent Binding Assay Reveals PIP2 Antagonism of TREK-1 Channels
Cell Reports, 2017 Lipid regulation of ion channels by low-abundance signaling lipids phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid (PA) has emerged as a central cellular mechanism for controlling ion channels and the excitability of nerves.
Cerrone Cabanos +3 more
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