Results 11 to 20 of about 2,675,614 (299)

Characterization of the lipid-binding properties and lipoprotein lipase inhibition of a novel apolipoprotein C-III variant Ala23Thr

open access: yesJournal of Lipid Research, 2000
We have identified a G-to-A transition in exon 3 of the APOC3 gene resulting in a novel Ala23Thr apolipoprotein (apo) C-III variant, associated with apoC-III deficiency in three unrelated Yucatan Indians.
Haiqun Liu   +9 more
doaj   +3 more sources

Elucidating the Lipid Binding Properties of Membrane-Active Peptides Using Cyclised Nanodiscs [PDF]

open access: yesFrontiers in Chemistry, 2019
The lipid composition of the cellular membrane plays an important role in a number of biological processes including the binding of membrane-active peptides.
Alan H. Zhang   +10 more
doaj   +2 more sources

Do Lipids Influence Gastrointestinal Processing: A Case Study of Major Soybean Allergen Gly m 4

open access: yesMembranes, 2021
Previously, we have demonstrated that Gly m 4, one of the major soybean allergens, could pass through the Caco-2 epithelial barrier and have proposed a mechanism of sensitization.
Ekaterina I. Finkina   +4 more
doaj   +1 more source

The Minor Matrix Protein VP24 from Ebola Virus Lacks Direct Lipid-Binding Properties

open access: yesViruses, 2020
Viral protein 24 (VP24) from Ebola virus (EBOV) was first recognized as a minor matrix protein that associates with cellular membranes. However, more recent studies shed light on its roles in inhibiting viral genome transcription and replication ...
Yuan Su, Robert V. Stahelin
doaj   +1 more source

Binding of Serotonin to Lipid Membranes [PDF]

open access: yesJournal of the American Chemical Society, 2013
Serotonin (5-hydroxytryptamine, 5-HT) is a prevalent neurotransmitter throughout the animal kingdom. It exerts its effect through the specific binding to the serotonin receptor, but recent research has suggested that neural transmission may also be affected by its nonspecific interactions with the lipid matrix of the synaptic membrane.
H. Peters, Günther   +5 more
openaire   +4 more sources

Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane

open access: yesViruses, 2020
Marburg virus (MARV) is a lipid-enveloped negative sense single stranded RNA virus, which can cause a deadly hemorrhagic fever. MARV encodes seven proteins, including VP40 (mVP40), a matrix protein that interacts with the cytoplasmic leaflet of the host ...
Kaveesha J. Wijesinghe   +7 more
doaj   +1 more source

The interaction of amyloid-β peptide with lipid membranes and glycosaminoglycans [PDF]

open access: yes, 2012
The aim of the thesis is a better understanding of the thermodynamics and structural aspects of the interaction of Aβ(1-40) with lipid membranes and glycosaminoglycans (GAGs).
Müller, Christian Thomas Benedikt
core   +1 more source

Salt Modulates the Stability and Lipid Binding Affinity of the Adipocyte Lipid-binding Proteins [PDF]

open access: yesJournal of Biological Chemistry, 2003
Adipocyte lipid-binding protein (ALBP or aP2) is an intracellular fatty acid-binding protein that is found in adipocytes and macrophages and binds a large variety of intracellular lipids with high affinity. Although intracellular lipids are frequently charged, biochemical studies of lipid-binding proteins and their interactions often focus most heavily
Allyn J, Schoeffler   +4 more
openaire   +2 more sources

The Lipopolysaccharide from Capnocytophaga canimorsus Reveals an Unexpected Role of the Core-Oligosaccharide in MD-2 Binding [PDF]

open access: yes, 2012
Capnocytophaga canimorsus is a usual member of dog's mouths flora that causes rare but dramatic human infections after dog bites. We determined the structure of C. canimorsus lipid A.
Marco Stenta (167214)   +37 more
core   +1 more source

Disruption of the C-terminal helix by single amino acid deletion is directly responsible for impaired cholesterol efflux ability of apolipoprotein A-I Nichinan

open access: yesJournal of Lipid Research, 2010
Apolipoprotein A-I (apoA-I) Nichinan, a naturally occurring variant with ΔE235 in the C terminus, is associated with low plasma HDL levels. Here, we investigated the tertiary structure, lipid-binding properties, and ability to induce cellular cholesterol
Momoe Kono   +9 more
doaj   +1 more source

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