Results 141 to 150 of about 2,154,580 (280)
Correction: Structural basis of phosphatidylcholine recognition by the C2-Domain of cytosolic phospholipase A<sub>2</sub>α. [PDF]
Hirano Y +8 more
europepmc +1 more source
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng +15 more
wiley +1 more source
The C2 domain of calpain 5 contributes to enzyme activation and membrane localization. [PDF]
Bondada V +6 more
europepmc +1 more source
Factor VIII C2 domain-specific inhibitory antibody epitopes and membrane binding models.
(A) Ribbon diagram representation of the fVIII C2 domain bound to different classes of C2-specific inhibitory antibodies. Each X-ray crystal structure was superimposed with the C2 domain structure and residues involved in the different epitopes are shown
Steven M. Mullen (702761) +8 more
core +1 more source
Membrane Targeting by C1 and C2 Domains [PDF]
openaire +2 more sources
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
Trinuclear Calcium Site in the C2 Domain of PKCα/γ Is Prone to Lithium Attack. [PDF]
Grauffel C, Weng WH, Dudev T, Lim C.
europepmc +1 more source
Gene synthesis, cloning, expression, purification and biophysical characterization of the C2 domain of human tensin [PDF]
Tensin is a large docking protein found in the adhesive junctions of animal cells and recruited early in the development of cell-substrate contacts. There it binds to the cytoplasmic domain of integrin β1 and caps the barbed ends of filamentous actin ...
Gajula, Kiran Sukumar
core
Atomic Tuning of Metal‐Support Interactions for Pathway‐Selective CO2 Photoreduction on TiO2
Single‐atom Fe and Cu catalysts anchored on TiO2 steer photocatalytic CO2 reduction toward distinct pathways. Fe sites favor rapid *CO desorption and selective CO formation, whereas Cu sites stabilize *CHO intermediates, enabling deep reduction and C─C coupling. Combined spectroscopy and DFT calculations reveal how metal–support interactions and oxygen
Dongyun Kim +13 more
wiley +1 more source
Structural insights into a C2 domain protein specifically found in tardigrades. [PDF]
Fukuda Y, Inoue T.
europepmc +1 more source

