Results 171 to 180 of about 157,972 (251)

WW and C2 domain-containing protein-3 promoted EBSS-induced apoptosis through inhibiting autophagy in non-small cell lung cancer cells. [PDF]

J Thorac Dis, 2020
Han Q, Rong X, Wang E, Liu S.
europepmc   +1 more source

Thermally Processable, Transparent, Mechanically Tunable and Robust Bioplastics From Wastepaper

Advanced Science, EarlyView.
Unlike conventional inefficient or low‐value wastepaper recycling, a directional transformation strategy is employed to convert whole wastepaper into intact bioplastics with tunable mechanical properties in our work. These bioplastics can be processed into flexible bags or rigid containers and exhibit high transparency, water resistance, repairability,
Zhezhe Zhou, Tao Chu, Boyou Hou, Mark Lynch, Siqi Huo, Min Hong, Jianguo Yang, Paulomi (Polly) Burey, Qiang Gao, Guobo Huang, Pingan Song   +10 more
wiley   +1 more source

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

Advanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su, Yanda Zhu, Hao Peng, Manman Li, Xuzihan Zhang, Meixiao Wu, Siyuan Zhang, Yuhan Zeng, Jiwen Liao, Ming Luo, Hetaishan Huang, Yutong Wang, Sean Li, Wenxian Li   +13 more
wiley   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

Confinement‐Driven CO Spillover in CuAg@MSN Tandem Catalysts Boosts C2 Selectivity Toward Electrocatalytic CO2 Reduction

Advanced Science, EarlyView.
The CuAg@MSN catalyst developed in this study promotes C─C coupling by regulating the coverage of *CO intermediates through spatial confinement effects, significantly enhancing the selectivity of CO2 electroreduction for C2 product formation. ABSTRACT Tandem catalysts represent a promising paradigm for synergistic electrochemical CO2 reduction (CO2RR ...
Jiaying Zhang, Junjie Huang, Siying Zhang, Yanjia Cui, Chao Kong, Zijian Peng, Huihui Jiang, Sirui Deng, Zhuoyao Chen, Caili Yang, Ketong He, Zhen Li, Yibing Song, Gongwei Wang, Lin Zhuang   +14 more
wiley   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

Electrocatalytic Coupling Conversion of Methane by Dual‐Site Control in Nickel Oxyhydroxide

Advanced Science, EarlyView.
Electrocatalytic coupling conversion of methane (CH4) is accomplished on the nickel oxyhydroxide (NiOOH), wherein the Ni─O dual‐site is triggered via the proper electronic interaction, synergistically promoting the C─H activation and C─C formation, enabling a selective and efficient C2 product generation route under ambient conditions. ABSTRACT Methane
Kailong Lu, Yangshen Chen, Junhao Wang, Yi Zhang, Sunyang He, Huimin Xu, Hui Liu, Jiao Deng   +7 more
wiley   +1 more source

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Brain‐Computer Interface Training Fosters Perceptual Skills to Detect Errors

Advanced Science, EarlyView.
Accurate perception of visuomotor errors underpins motor precision and learning, yet conventional behavioral training fails to improve sensitivity to subtle errors. Real‐time EEG‐based brain‐computer interface feedback targeting the error positivity component enhances perceptual learning of small errors.
Deland H. Liu, Fumiaki Iwane, Minsu Zhang, Leonardo G. Cohen, José del R. Millán   +4 more
wiley   +1 more source

Retinomorphic Visual Processing Enabled by Contact‐Engineered IGZO Optoelectronic Synaptic Memtransistors

Advanced Science, EarlyView.
Here, we present an optoelectronic synaptic memtransistor (OSMT) integrating photoresponsive IGZO with contact‐engineered HfO2, enabling electrically and optically tunable synaptic weights. The device demonstrates broad range of tunable conductance states and array‐level image processing, highlighting its potential for intelligent machine vision ...
Donghyun Kang, San Nam, Dayul Nam, In‐Soo Kim, Myung‐Gil Kim, Sung Kyu Park, Yong‐Hoon Kim   +6 more
wiley   +1 more source