Results 11 to 20 of about 27,277 (237)

C3aR Antagonist Alleviates C3a Induced Tubular Profibrotic Phenotype Transition via Restoring PPARα/CPT-1α Mediated Mitochondrial Fatty Acid Oxidation in Renin-Dependent Hypertension

Frontiers in Bioscience-Landmark, 2023
Background: Renin-dependent hypertension with tubulointerstitial injury remains a problem with high prevalence in the clinic. However, whether and how renin participates in tubulointerstitial injury remains incompletely understood.
Chongjian Wang, Zhiyu Wang, Jing Xu, Hongkun Ma, Kexin Jin, Tingting Xu, Xiaoxia Pan, Xiaobei Feng, Wen Zhang   +8 more
doaj   +1 more source

Cluster-Zone Leaf Removal and GA₃ Application at Early Flowering Reduce Bunch Compactness and Yield per Vine in Vitis vinifera cv. Pinot Gris

Horticulturae, 2022
Compact bunches have been often associated with higher susceptibility to Botrytis cinerea and therefore reduction in berry quality in grapevine. The objective of this study was to evaluate three management methods (early leaf removal, gibberellic acid ...
Mario Wegher, Michele Faralli, Massimo Bertamini   +2 more
doaj   +1 more source

Complement C3 and Activated Fragment C3a Are Involved in Complement Activation and Anti-Bacterial Immunity

Frontiers in Immunology, 2022
In the complement system, C3 is a central component in complement activation, immune defense and immune regulation. In all pathways of complement activation, the pivotal step is conversion of the component C3 to C3b and C3a, which is responsible to ...
Meng Wu, Bei-bei Jia, Mo-fei Li
semanticscholar   +1 more source

A novel approach to immunoapheresis of C3a/C3 and proteomic identification of associates [PDF]

PeerJ, 2019
Background Complement factor C3 represents the central component of the complement cascade and its activation split product C3a plays an important role in inflammation and disease. Many human disorders are linked to dysregulation of the complement system
Wolfgang Winnicki, Peter Pichler, Karl Mechtler, Richard Imre, Ines Steinmacher, Gürkan Sengölge, Daniela Knafl, Georg Beilhack, Ludwig Wagner   +8 more
doaj   +2 more sources

Influence of Sulfates on Formation of Ettringite during Early C3A Hydration

Materials, 2022
The hydration of C3A-gypsum systems was studied in the presence of various types of sulfates such as gypsum, hemihydrate and Na2SO4 in the first hour.
Yong Yang, Qianqian Zhang, X. Shu, Xiumei Wang, Q. Ran   +4 more
semanticscholar   +1 more source

The complement C3a-C3aR and C5a-C5aR pathways promote viability and inflammation of human retinal pigment epithelium cells by targeting NF-κB signaling

Experimental and Therapeutic Medicine, 2022
Retinal detachment (RD) and its special form of rhegmatogenous RD associated with choroidal detachment (RRDCD) feature similar pathological alterations, including enhanced retinal cell inflammation.
Shasha Luo, Huiyan Xu, Xuechun Gong, Jinyan Shen, Xuan Chen, Zhifeng Wu   +5 more
semanticscholar   +1 more source

The association between serum complement C3a and severity in patients with community-acquired pneumonia

Frontiers in Immunology, 2023
BackgroundA few studies found that the complement system may be involved in the onset and progression of community-acquired pneumonia (CAP). However, the role of the complement system in CAP was obscure.
Zheng Xu, Zheng Xu, Zheng Xu, Xue-Feng Hou, Chun-Mei Feng, Ling Zheng, De-Xiang Xu, Hui Zhao, Hui Zhao, Lin Fu, Lin Fu, Lin Fu   +11 more
doaj   +1 more source

Epidemiology and control of strawberry powdery mildew: a review

Phytopathologia Mediterranea, 2023
Strawberry powdery mildew, caused by Podosphaera aphanis, is an economically important disease for strawberry production. Typical symptoms are white mycelium on all aerial parts of affected plants, with young host tissues being the most susceptible.
Anna ALDRIGHETTI, Ilaria PERTOT
doaj   +1 more source

Human platelet activation by C3a and C3a des-arg. [PDF]

The Journal of experimental medicine, 1983
C3a liberated from C3 by treatment with C3 convertase (or by trypsin) induced aggregation of gel-filtered human platelets and stimulated serotonin release. At concentrations of 10(-10) M to 8 X 10(-12) M, C3a induced aggregation when added alone to platelets.
M J, Polley, R L, Nachman
openaire   +2 more sources

Increased ratios of complement factors C3a to C3 in aqueous humor and serum mark glaucoma progression.

Experimental Eye Research, 2021
INTRODUCTION We recently performed a combined analysis of publicly available proteomic studies of aqueous humor (AH) of patients with primary open angle glaucoma (POAG).
W. Hubens, H.J.M. Beckers, T. Gorgels, C. Webers   +3 more
semanticscholar   +1 more source