Results 31 to 40 of about 26,236 (223)

The role of complement components (C1q, C3a, MAC) activation in earlyand late-onset preeclampsia and fetal growth restriction

Акушерство, гинекология и репродукция
Introduction. Preeclampsia (PE) remains one of the leading causes for maternal and perinatal morbidity and mortality. Placental insufficiency associated with impaired trophoblast invasion, hypoperfusion, and inflammatory endothelial activation is ...
A. S. Antonova, M. V. Tretyakova, J. Kh. Khizroeva, V. O. Bitsadze, N. F. Kuneshko, S. Morkos, I. S. Kalashnikova, N. Rouzy, G. Gerotziafas, I. Elalamy, A. D. Makatsariya   +10 more
doaj   +1 more source

Complement inhibition promotes endogenous neurogenesis and sustained anti-inflammatory neuroprotection following reperfused stroke. [PDF]

PLoS ONE, 2012
The restoration of blood-flow following cerebral ischemia incites a series of deleterious cascades that exacerbate neuronal injury. Pharmacologic inhibition of the C3a-receptor ameliorates cerebral injury by attenuating post-ischemic inflammation. Recent
Andrew F Ducruet, Brad E Zacharia, Sergey A Sosunov, Paul R Gigante, Mason L Yeh, Justin W Gorski, Marc L Otten, Richard Y Hwang, Peter A DeRosa, Zachary L Hickman, Paulina Sergot, E Sander Connolly   +11 more
doaj   +1 more source

Complement components C3a promoted tumor recurrence after liver transplantation

, 2021
Introduction: Complement components are the keys regulators orchestrating many cellular responses including immunological responses. Increasing evidences showed complement components involved in many liver pathology.
Lo, CM, Liu, H, Man, K, Yeung, WHO, Ng, TPK   +4 more
core   +1 more source

Complement C3a activates osteoclasts by regulating the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma

Cancer Biology & Medicine, 2021
Objective: Myeloma bone disease (MBD) is the most common complication of multiple myeloma (MM). Our previous study showed that the serum levels of C3/C4 in MM patients were significantly positively correlated with the severity of bone disease.
Fengjuan Jiang, Hui Liu, Fengping Peng, Zhaoyun Liu, Kai Ding, Jia Song, Lijuan Li, Jin Chen, Qing Shao, Siyang Yan, Kim De Veirman, Karin Vanderkerken, Rong Fu   +12 more
doaj   +1 more source

Current understanding of cellulose ethers impact on the hydration of C3A and C3A-sulphate systems [PDF]

, 2009
International audienceThe impact of cellulose ethers (CE) on C3A hydration was examined to support the understanding of the retarding effect of CE on cement hydration.
Grosseau, Philippe, Ruot, Bernard, Pourchez, Jérémie   +2 more
core   +1 more source

Plasmin degrades C3a.

, 2013
(A) C3a was completely degraded by plasmin; plasminogen had a weak degrading effect. S. aureus was incubated with C3a in the presence of plasmin (PLG+SAK) (lane 4) or plasminogen alone (lane 6). The supernatants were analyzed by SDS-PAGE and Western blot
Tina K. Koch (303277), Jean van den Elsen (268290), Peter Kraiczy (36173), Christine Skerka (105424), Michael Reuter (268288), Sascha Böhm (303280), Peter F. Zipfel (105431), Diana Barthel (303279)   +7 more
core   +1 more source

Complement receptor C3aR marks heterogeneous tumor-associated macrophage states associated with improved survival in IDH-wildtype glioblastoma. [PDF]

Brain Pathol
C3aR expression in IDH‐wildtype glioblastoma is predominantly associated with the myeloid/macrophage compartment and heterogeneous macrophage states. C3aR‐high tumors are enriched among MGMT promoter‐methylated tumors and show improved overall survival, although the prognostic association requires independent validation.
Imara M, Bedoui Y, Pignolet T, Freppel S, Brochard C, Delattre A, Cappellen D, Bauchet L, Khettab M, Ah-Pine F.   +9 more
europepmc   +2 more sources

Vibrational Signals for Mating Disruption Do Not Negatively Affect Grapevine Growth and Production

Australian Journal of Grape and Wine Research
Vibrational mating disruption (VMD) is a promising strategy to control Scaphoideus titanus populations in vineyards, and it is based on the prolonged application of a species-specific disturbance vibrational signal (DVS) on grapevines.
Stefano Galvagni, Michele Perazzolli, Mauro Varner, Valerio Mazzoni, Gianfranco Anfora, Michele Faralli, Rachele Nieri   +6 more
doaj   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

Synergistic Effects of Tricalcium Aluminate and Gypsum on Performance of Oil Well Cement Slurries

Zuanjingye yu wanjingye
To better control the quality of oil well cement, class G cement clinkers with different contents of tricalcium aluminate (C3A) were mixed with different kinds of gypsums, and study was conducted on the synergistic effects of C3A and gypsum on the ...
Dan DAI, Yixin WANG, Yiwei ZOU, Chao SUN, Ying MA, Xinjun SONG   +5 more
doaj   +1 more source