Anaphylatoxin C3a receptors in asthma [PDF]
Respiratory Research, 2005 The complement system forms the central core of innate immunity but also mediates a variety of inflammatory responses. Anaphylatoxin C3a, which is generated as a byproduct of complement activation, has long been known to activate mast cells, basophils ...
Panettieri Reynold A, Ali Hydar
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Modulation of human lymphocyte function by C3a and C3a(70-77). [PDF]
The Journal of experimental medicine, 1982 Human C3a and the synthetic octapeptide C3a (70-77), which retains the activities of an anaphylatoxin, inhibit in a concentration-dependent manner the generation of leukocyte inhibitory factor (LIF) activity by human mononuclear leukocytes and T ...
Goetzl, EJ, Payan, DG, Trentham, DE
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Current understanding of cellulose ethers impact on the hydration of C3A and C3A-sulphate systems [PDF]
Cement and Concrete Research, 2009 International audienceThe impact of cellulose ethers (CE) on C3A hydration was examined to support the understanding of the retarding effect of CE on cement hydration.
Grosseau, Philippe +2 more
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Cytolysis of fibroblasts by C3a [PDF]
British Journal of Cancer, 1980 C3a was found to be more cytolytic to transformed than to primary fibroblast cultures from mouse and man. Fibroblasts made quiescent with caffeine were lysed by the same concentrations of C3a as untreated cells. These findings may have implications in tumour immunity.
A, Temple, A C, Allison
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Human platelet activation by C3a and C3a des-arg. [PDF]
The Journal of experimental medicine, 1983 C3a liberated from C3 by treatment with C3 convertase (or by trypsin) induced aggregation of gel-filtered human platelets and stimulated serotonin release. At concentrations of 10(-10) M to 8 X 10(-12) M, C3a induced aggregation when added alone to platelets.
M J, Polley, R L, Nachman
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Investigation of the Incompatibilities of Cement and Superplasticizers and Their Influence on the Rheological Behavior [PDF]
, 2020 The rheological behavior of cement paste and the improvement of its flowability takes center stage in many research projects. An improved flowability can be achieved by the addition of superplasticizers (SP), such as polycarboxylate ethers (PCE).
Jakob, Cordula +4 more
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Complement C3a Enhances the Phagocytic Activity of B Cells Through C3aR in a Fish
Frontiers in Immunology, 2022 The complement system is an important part of the immune system of teleost fish. Besides, teleost B cells possess both phagocytic activity and adaptive humoral immune function, unlike mammalian B1 cells with phagocytic activity and B2 cells specific to ...
Zi-You Ma +19 more
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Complement 3a and Complement 5a as Biochemical Markers in Diabetic Nephropathy [PDF]
International Journal of Medical ArtsBackground: Diabetes mellitus [DM] is growing into a global epidemic and diabetic nephropathy [DN] is one of its most feared complications. Inflammation is an important mechanism in the pathogenesis of DN and many studies have pointed to anaphylatoxins ...
Safwat Ahmed +3 more
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A Scanning Transmission X-ray Microscopy Study of Cubic and Orthorhombic C₃A and Their Hydration Products in the Presence of Gypsum. [PDF]
, 2016 This paper shows the microstructural differences and phase characterization of pure phases and hydrated products of the cubic and orthorhombic (Na-doped) polymorphs of tricalcium aluminate (C₃A), which are commonly found in traditional Portland cements ...
Chae, Sejung Rosie +5 more
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C3aR plays both sides in regulating resistance to bacterial infections.
PLoS Pathogens, 2022 Activation of the complement pathway results in the production of bioactive C3a, a product of C3 cleavage, which interacts with membrane-bound receptor C3aR to regulate innate immune cell function and outcome of bacterial infection.
Jesse A Corcoran, Brooke A Napier
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