Modulation of human lymphocyte function by C3a and C3a(70-77). [PDF]
Human C3a and the synthetic octapeptide C3a (70-77), which retains the activities of an anaphylatoxin, inhibit in a concentration-dependent manner the generation of leukocyte inhibitory factor (LIF) activity by human mononuclear leukocytes and T lymphocytes cultured with the mitogens phytohemagglutinin (PHA) or concanavalin A (Con A) or the antigen ...
Payan, DG, Trentham, DE, Goetzl, EJ
openaire +7 more sources
Antifungal activity of C3a and C3a-derived peptides against Candida [PDF]
Antimicrobial peptides are generated during activation of the complement system [Nordahl et al. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:16879-16884]. Here we show that the anaphylatoxin C3a exerts antimicrobial effects against the yeast Candida. Fluorescence microscopy and electron microscopy analysis demonstrated that C3a-derived peptides bound to ...
Sonesson, Andreas +5 more
openaire +3 more sources
Influence of Lithium Carbonate on C3A Hydration [PDF]
Lithium salts, known to ameliorate the effects of alkali-silica reaction, can make significant effects on cement setting. However, the mechanism of effects on cement hydration, especially the hydration of C3A which is critical for initial setting time of
Weiwei Han +5 more
doaj +2 more sources
C3a is made by proximal tubular HK-2 cells and activates them via the C3a receptor [PDF]
Some individual components of complement are synthesized by the kidney. However, it is not known whether these form functional pathways that are able to mediate more fundamental cellular events. We examined the ability of HK-2 tubular cells to produce an intact alternative pathway of complement and to respond to the C3a fragment thus produced through ...
Peake, Philip W. +3 more
openaire +4 more sources
Human Plasmacytoid Dendritic Cells Express Receptors for Anaphylatoxins C3a and C5a and Are Chemoattracted to C3a and C5a [PDF]
The presence of plasmacytoid dendritic cells (pDC) was recently demonstrated in lesions of inflammatory skin diseases. Since anaphylatoxins or their precursors were also found in such lesions, we investigated a possible interaction between pDC and anaphylatoxins C3a and C5a.
Gutzmer, Ralf +6 more
openaire +5 more sources
Current understanding of cellulose ethers impact on the hydration of C3A and C3A-sulphate systems [PDF]
The impact of cellulose ethers (CE) on C3A hydration was examined to support the understanding of the retarding effect of CE on cement hydration. In this sense, we successively studied the CE adsorption on ettringite and calcium hydroaluminates, and then the CE influence during C3A hydration in presence or absence of calcium sulphate.
Pourchez, Jérémie +2 more
openaire +4 more sources
C3a Enhances the Formation of Intestinal Organoids through C3aR1 [PDF]
C3a is important in the regulation of the immune response as well as in the development of organ inflammation and injury. Furthermore, C3a contributes to liver regeneration but its role in intestinal stem cell function has not been studied.
Naoya Matsumoto +7 more
doaj +2 more sources
Synthesis of C6A-to-C6A and C3A-to-C3A diamide linked γ-cyclodextrin dimers [PDF]
Abstract The syntheses of three new diamide-linked γ-cyclodextrin dimers joined by substitution at either a glucopyranose C6 A or C3 A carbon are reported. The syntheses involve the reaction of either C6 A or C3 A amino-substituted γ-cyclodextrin with bis(4-nitrophenyl)succinate to form succinamide linked γ-cyclodextrin dimers or reaction of C6 A
Pham, Duc-Truc +4 more
openaire +3 more sources
C3a/C3 immunoblot developed with 3F7E2 mAb. [PDF]
Twenty times (20x) concentrated urine from a patient with high C3a/C3 level in urine ELISA (lane 1); ten times (10x) concentrated urine from a patient with medium range C3a/C3 level in urine ELISA (lane 2); three times (3x) concentrated urine from ...
Sebastian Kapps (9979115) +7 more
core +1 more source
A novel approach to immunoapheresis of C3a/C3 and proteomic identification of associates [PDF]
Background Complement factor C3 represents the central component of the complement cascade and its activation split product C3a plays an important role in inflammation and disease. Many human disorders are linked to dysregulation of the complement system
Wolfgang Winnicki +8 more
doaj +2 more sources

