Results 121 to 130 of about 853,917 (241)

Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System

open access: yesAdvanced Science, EarlyView.
This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao   +7 more
wiley   +1 more source

Site of Deposition of C3 in Arthus Reactions of C4 Deficient Guinea Pigs [PDF]

open access: bronze, 1973
Michael M. Frank   +3 more
openalex   +1 more source

C4 olefin conversion on reduced nickel y faujasite. Evidence for C5 olefin formation via C4 olefin disproportionation [PDF]

open access: yes, 1984
A. Barth   +15 more
core   +1 more source

Gradient Nanostructures and Machine Learning Synergy for Robust Quantitative Surface‐Enhanced Raman Scattering

open access: yesAdvanced Science, EarlyView.
A novel SERS platform using gradient nanostructures and machine learning is presented. Gradient nanostructures minimize fabrication variability and enhance spectral diversity. The ML model significantly improves quantification precision, robustness and reproducibility, reducing test MSE by 84.8% and increasing R2 by 61.2%, enabling reliable real‐world ...
Xiaoyu Zhao   +13 more
wiley   +1 more source

Immunochemical Quantitation of Cell Bound C4 [PDF]

open access: bronze, 1974
Sarkis H. Ohanian, Tibor Borsos
openalex   +1 more source

Nano/Micro Metal‐Organic Framework‐Derived Porous Carbon with Rich Nitrogen Sites as Efficient Iodine Hosts for Aqueous Zinc‐Iodine Batteries

open access: yesAdvanced Science, EarlyView.
A cubic zinc‐based metal‐organic framework derived (Zn‐MOF‐derived) porous nitrogen‐doped carbon host is engineered to immobilize iodine, leveraging its hierarchical porosity and rich nitrogen sites to suppress polyiodide shuttling and enhance redox kinetics in zinc–iodine (Zn–I2) batteries.
Yong Li   +8 more
wiley   +1 more source

Isolation of Human C4 by Affinity Chromatography with IgG-Coupled Sepharose 6B [PDF]

open access: bronze, 1973
Richard A. Patrick   +2 more
openalex   +1 more source

Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells

open access: yesAdvanced Science, EarlyView.
Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng   +14 more
wiley   +1 more source

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