Results 141 to 150 of about 364,632 (296)

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

open access: yesAdvanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan   +8 more
wiley   +1 more source

Photosynthetic responses of three C4 grasses of different metabolic subtypes to water deficit

open access: yes, 2007
C4 plants are considered to be less sensitive to drought than C3 plants because of their CO2 concentrating mechanism. The C4 grasses, Paspalum dilatatum Poiret (NADP-ME), Cynodon dactylon (L.) Pers (NAD-ME) and Zoysia japonica Steudel (PEPCK) were ...
Bernardes Da Silva, A.   +11 more
core   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo   +13 more
wiley   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

open access: yesAdvanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang   +13 more
wiley   +1 more source

Ultrabroadband and Highly Sensitive Short‐Wave Infrared Molecular Fingerprinting via Acoustic MXene Plasmons

open access: yesAdvanced Science, EarlyView.
Acoustic plasmons in Ti3C2Tx MXene strongly compress infrared electromagnetic fields and enhance light–matter interactions at the nanoscale. This platform couples broadband plasmon excitations with molecular vibrations, enabling simultaneous sensing of high‐ and low‐frequency vibrational modes in ultrathin PMMA and graphene oxide films, and extending ...
Changhoon Park   +7 more
wiley   +1 more source

Accelerated Numerical Simulations of a Reaction-Diffusion- Advection Model Using Julia-CUDA

open access: yesMathematics
The emergence of exascale computing systems presents both opportunities and challenges in scientific computing, particularly for complex mathematical models requiring high-performance implementations.
Angelo Ciaramella   +3 more
doaj   +1 more source

Carbon isotope and C/N ratios of suspended matter in rivers: An indicator of seasonal change in C4/C3 vegetation

open access: yes, 2003
     A combination of d 13C values with C/N ratios in suspended matter has been used to examine the seasonal relationshipbetween C4 and C3 vegetation along the Loess Plateau, NW China.
D.L. Cai   +9 more
core   +1 more source

Wireless, Adaptable and Fully Implantable Battery‐powered Devices for Optical Stimulation of the Spinal Cord in Small Rodents

open access: yesAdvanced Science, EarlyView.
Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh   +8 more
wiley   +1 more source

Thermoelectric Gating Organic Electrochemical Transistors Enabled by Printable Ionogels With n‐p Convertible Thermopower

open access: yesAdvanced Science, EarlyView.
A type of thermoelectric ionogels with convertible n‐p thermopowers are demonstrated with Seebeck coefficients ranging from ‐3.61 to +9.74 mV K−1. Thus, thermoelectric gating organic electrochemical transistor is achieved by employing ionogel as thermoelectric modules and ionic dielectrics simultaneously, paving the road to self‐powered, highly ...
Xingyu Hu   +8 more
wiley   +1 more source

Electrochemical Modulation of Laser‐Induced Covalent Functionalization of Graphene

open access: yesAdvanced Science, EarlyView.
Photoelectrochemical functionalization of graphene introduces the electrochemical potential as an additional parameter for the laser‐induced covalent modification of graphene. Tuning of the potential allows for amplification or suppression of the functionalization reaction with constant laser parameters, which enables in situ Raman analysis of ...
Tamara Nagel   +7 more
wiley   +1 more source

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