Results 161 to 170 of about 1,192,546 (345)

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Kinetic Modeling Study on the Combustion Characterization of Synthetic C3 and C4 Alcohols for Lean Premixed Prevaporized Combustion [PDF]

, 2021
Solmaz Nadiri, Paul Zimmermann, Laxmi Sane, Ravi X. Fernandes, Friedrich Dinkelacker, Bo Shu   +5 more
openalex   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Regulation of complement activity by immunoglobulin. I. Effect of immunoglobulin isotype on C4 uptake on antibody-sensitized sheep erythrocytes and solid phase immune complexes [PDF]

, 1996
V Miletić, C. Garren Hester, Magdalena Frank   +2 more
openalex   +1 more source

Newly emerged enterovirus-A71 C4 sublineage may be more virulent than B5 in the 2015–2016 hand-foot-and-mouth disease outbreak in northern Vietnam [PDF]

, 2020
Son T. Chu, Kyousuke Kobayashi, Xiuqiong Bi, Azumi Ishizaki, Tu Thanh Tran, Thuy Thi Bich Phung, Chung T. T. Pham, Lam Van Nguyen, Ta Anh Tuan, Dung Thi Khanh Khu, Masanobu Agoh, An N. Pham, Satoshi Koike, Hiroshi Ichimura   +13 more
openalex   +1 more source

Investigating Mitochondrial Viscosity in Ferroptosis‐Mediated Drug‐Induced Liver Injury using a Double‐Targeted Strategy

Advanced Science, EarlyView.
Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou, Yan Wang, Bing Huang, Hosoowi Lee, Mei Yan, Juyoung Yoon   +5 more
wiley   +1 more source

Nonspecific phospholipases C3 and C4 interact with PIN-FORMED2 to regulate growth and tropic responses in Arabidopsis [PDF]

T. Li, Shujuan Zhang, Shuaibing Yao, X Li, Qianru Jia, Jingya Yuan, Wenhua Zhang, Xuemin Wang, Qun Zhang   +8 more
openalex   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

OKUL%20Y%c3%96NET%c4%b0C%c4%b0LER%c4%b0N%c4%b0N%20L%c4%b0DERL%c4%b0K%20ST%c4%b0L%c4%b0%20%c3%96L%c3%87E%c4%9e%c4%b0N%c4%b0N%20GEL%c4%b0%c5%9eT%c4%b0R%c4%b0LMES%c4%b0

International Journal of Social Humanities Sciences Research (JSHSR), 2018
openaire   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source