Characterization of human C4a anaphylatoxin.
Human C4a anaphylatoxin was isolated from a Cls digest of the fourth component of complement. Isolation required a two-step procedure involving ion-exchange chromatography on CM-Sephadex C-50 and gel filtration on Sephadex G-50. Characterization of C4a indicated it is a highly cationic polypeptide (pI = 9.0-9.5) containing 77 residues with Mr = 8,759 ...
J P, Gorski +2 more
openaire +2 more sources
1,2-Dimethyl-4,5-diphenylbenzene determined on a Bruker SMART X2S benchtop crystallographic system [PDF]
The title compound, C(20)H(18), has two crystallographically independent molecules in the asymmetric unit. The phenyl substituents of molecule A are twisted away from the plane defined by the central benzene ring by 131.8 (2) and -52.7 (3)degrees.
Briggs, Jonathan B +2 more
core +1 more source
Genetically predicted complement component 4A expression: effects on memory function and middle temporal lobe activation [PDF]
Background The longstanding association between the major histocompatibility complex (MHC) locus and schizophrenia (SZ) risk has recently been accounted for, partially, by structural variation at the complement component 4 (C4) gene.
A. Corvin +13 more
core +3 more sources
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You +12 more
wiley +1 more source
Crystal structure of \u3cem\u3ecis\u3c/em\u3e-2-(2-carboxycyclopropyl)-glycine (CCG-III) monohydrate [PDF]
The title compound, C6H9NO4·H2O [systematic name: (αR,1R,2S)-rel-α-amino-2-carboxycyclopropaneacetic acid monohydrate], crystallizes with two organic molecules and two water molecules in the asymmetric unit.
Donaldson, William A. +2 more
core +1 more source
Vanishing of the four-loop charge renormalization function in N=4 SYM theory
We calculate the renormalization constants of the maximally extended N=4 supersymmetric Yang-Mills theories in the dimensional reduction scheme up to four loops. We have found, that the beta-function is zero both from gauge and Yukawa vertices.Comment: 6
Velizhanin, V. N.
core +1 more source
Intermolecular Dehydrative Coupling Reaction of Arylketones with Cyclic Alkenes Catalyzed by a Well-Defined Cationic Ruthenium-Hydride Complex: A Novel Ketone Olefination Method via Vinyl C–H Bond Activation [PDF]
The cationic ruthenium−hydride complex [(η6-C6H6)(PCy3)(CO)RuH]+BF4− was found to be a highly effective catalyst for the intermolecular olefination reaction of aryl ketones with cycloalkenes.
Lee, Do W., Yi, Chae S.
core +2 more sources
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li +22 more
wiley +1 more source
Analysis of cross-reactive neutralizing antibodies in human HFMD serum with an EV71 pseudovirus-based assay. [PDF]
Hand, foot and mouth disease, associated with enterovirus 71 (EV71) infections, has recently become an important public health issue throughout the world.
Huafei Zhang +19 more
doaj +1 more source
(1R,2S)-Methyl 1-(4-chloro-phen-yl)-3-oxo-1,2,3,4-tetra-hydro-cyclo-penta-[b]indole-2-carboxyl-ate 0.2-hydrate [PDF]
The title compound, C(19)H(14)ClNO(3)·0.2H(2)O, crystallizes with five mol-ecules and a disordered water mol-ecule in the asymmetric unit. Four of the five mol-ecules form hydrogen-bonded dimers via N-H⋯O hydrogen bonds towards another symmetry ...
Bolte, Michael, Raja, Sadiya
core +3 more sources

