Results 131 to 140 of about 6,868 (161)

The Immune Microenvironment of Transplant Glomerulitis. [PDF]

open access: yesKidney Int Rep
Bracey NA   +10 more
europepmc   +1 more source

Complement in Antibody-Mediated Rejection of the Kidney Graft: From Pathophysiology to Clinical Practice. [PDF]

open access: yesJ Clin Med
Sorohan BM   +7 more
europepmc   +1 more source

Glomerulitis and endothelial cell enlargement in C4d+ and C4d− acute rejections of renal transplant patients

Human Pathology, 2012
In acute rejection after renal transplant, glomerulitis is characterized by mononuclear cells in glomerular capillaries and endothelial cell enlargement. In association with C4d deposition in peritubular capillaries, glomerulitis is a feature of acute antibody-mediated rejection. Prognosis in C4d(+) rejection is poorer than in C4d(-) rejection.
Aiello FB   +9 more
openaire   +3 more sources

C4d—The Witness of Humoral Rejection

Transplantation Proceedings, 2009
Acute antibody-mediated (humoral) rejection is a major cause of morbidity, graft loss, and mortality among heart transplant patients. Herein we have presented our experience using C4d to characterize humoral rejection.All nonformalin-fixed cardiac graft biopsies (protocol or emergency) received between May 2007 and May 2008 were examined by ...
R H, de Gouveia   +6 more
openaire   +2 more sources

C4d Immunohistochemistry in glomerulonephritis with different antibodies

Clinical and Experimental Nephrology, 2007
The presence of C4d in the kidney is generally detected particularly for the diagnosis of antibody-mediated rejection in renal transplants. In frozen sections of immunofluorescence (IF) staining with anti-C4d monoclonal antibodies (mAbs), we noted intrinsic C4d deposition even in normal glomeruli though their pathogenic or an intrinsic role is unkown ...
Taisei, Suzuki   +7 more
openaire   +2 more sources

C4d in Native Glomerular Diseases

American Journal of Nephrology, 2019
Complement activation occurs in many glomerular diseases, the exact pathway(s) of activation has been studied in detail in some diseases but not in all. C4d is generated by the activation of classical and lectin pathways, and its presence can point to the activation of either of these pathways.
openaire   +2 more sources

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