Results 141 to 150 of about 256,837 (255)

Dynamic Behavioral Profiling for User Authentication Using Binary Pressure Sequences and Grip Patterns via a Soft Stacking Ensemble

open access: yesAdvanced Intelligent Systems, EarlyView.
A smartphone‐embedded fabric‐strip sensing interface captures side‐pressure sequences and grip‐position patterns for behavioral authentication. Probability‐based soft stacking integrates class‐wise predictive probabilities from multiple learners to improve verification‐style discrimination, supporting a sensor‐integrated mobile‐security framework that ...
Wonki Hong
wiley   +1 more source

Using pre‐ and post‐entry data to identify the effect of ethanol plant entry on the spatial pattern of corn prices: A study in Indiana

open access: yesAmerican Journal of Agricultural Economics, EarlyView.
Abstract We estimate the long‐run effect of ethanol plant entry on local corn prices using a long‐horizon difference‐in‐differences framework that combines matching with fixed effects while explicitly accounting for treatment intensity and spatial heterogeneity.
Jinho Jung   +2 more
wiley   +1 more source

Aromatic Pummerer‐Promoted Stereospecific Cross‐Coupling of Thiazoles With Boronic Esters

open access: yesAngewandte Chemie, EarlyView.
A lithiation–borylation–aromatic Pummerer (LiBAP) strategy enables stereospecific, C5‐selective C(sp2)–C(sp3) cross‐coupling of thiazoles with boronic esters. By using exocyclic sulfoxide activation to overcome the low nucleophilicity that frustrates SEAr‐type coupling, the method delivers enantioenriched alkylated thiazoles bearing a versatile C2 ...
Mark John P. Mandigma   +4 more
wiley   +2 more sources

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

open access: yesAnnals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca   +24 more
wiley   +1 more source

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

open access: yesAngewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley   +11 more
wiley   +2 more sources

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

open access: yesAnnals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer   +14 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

Apocynin: Molecular Aptitudes

open access: yesMediators of Inflammation, 2008
J. Stefanska, R. Pawliczak
doaj   +1 more source

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