Results 71 to 80 of about 256,837 (255)

Infrastructure project cost overrun and schedule delay in Ghana: Is it an issue of resource misallocation or financial constraints?

Project Leadership and Society
This study investigates the cost overrun and schedule delay of four major infrastructure projects in the Greater Accra Region of Ghana. The study collected data from 201 project staff and managers.
Doe Precious
doaj   +1 more source

FERNET-C5

, 2021
The FERNET-C5 is a monolingual BERT language representation model trained from scratch on the Czech Colossal Clean Crawled Corpus (C5) data - a Czech mutation of the English C4 dataset. The training data contained almost 13 billion words (93 GB of text data). The model has the same architecture as the original BERT model, i.e. 12 transformation blocks,
Lehečka, Jan, Švec, Jan
openaire   +1 more source

Calculation of C5 Stresses and Deflections in C5 Due to Thermal and Pressure Loading. [PDF]

, 2008
This report talks about Calculation of C5 Stresses and Deflections in C5 Due to Thermal and Pressure ...
Guarino, V.
core   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Toward responsible investment: A deep learning frame-work for ESG-differentiated portfolio optimization

Journal of Economics and Management
Aim/purpose – This paper proposes a framework that integrates deep learning-based return forecasting with environmental, social, and governance (ESG)-differentiated optimization to align portfolio performance with financial and sustainability goals ...
Nguyen Minh Duc
doaj   +1 more source

C5-Hydroxylation of Liquirtigenin Is Catalyzed Selectively by CYP1A2

, 2010
C5-Hydroxylation of Liquirtigenin Is Catalyzed Selectively by ...
胡莹, 杨凌, 刘慧鑫
core  

Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction

Advanced Science, EarlyView.
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen, Bapan Biswas, Apinya Ngoipala, Julia Wiktor, Ujjwal Pal, Shalini Singh   +5 more
wiley   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Sort communication. Genotype × environment interaction analysis in two chickpea RIL populations

Spanish Journal of Agricultural Research, 2013
In order to introduce new chickpea germplasm in Argentina, two recombinant inbred line (RIL) populations F6:7 of twenty lines, each one derived from crosses between kabuli and desi types, were evaluated for yield components in different sites and years ...
J. Carreras, J. Rubio, F. Flores, T. Millan, J. Gil   +4 more
doaj   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source