Results 71 to 80 of about 239,366 (193)

Galactic very high energy sources and enhancements of material content

EPJ Web of Conferences, 2015
The association of very-high energy (VHE; E > 100 GeV) sources with regions of the sky rich in dust and gas has been noticed in the study of individual VHE sources. However, the statistical significance of this correlation for the whole population of TeV
Pedaletti Giovanna, de Oña Wilhelmi Emma, Torres Diego F., Natale Giovanni   +3 more
doaj   +1 more source

Structural basis for therapeutic inhibition of complement C5.

, 2016
Activation of complement C5 generates the potent anaphylatoxin C5a and leads to pathogen lysis, inflammation and cell damage. The therapeutic potential of C5 inhibition has been demonstrated by eculizumab, one of the world's most expensive drugs. However,
Elmlund, H, Yang I Li, Johnson, S, Nunn, MA, Johnson, Steven, Jore, Matthijs M., Li, Yang I., Susan M Lea, Lea, SM, Natalie M Barber, Devon Sheppard, Lea, Susan M., Li, YI, Sheppard, Devon, Barber, Natalie M., Steven Johnson, Miles A Nunn, Matthijs M Jore, Barber, NM, Elmlund, Hans, Jore, MM, Nunn, Miles A., Sheppard, D, Hans Elmlund   +23 more
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The Influence of the Capital Market (Financial Instruments) on Economic Growth in Kazakhstan and CIS Countries

ECONOMICS
Econometrics is a branch of economics that uses mathematical and statistical methods to study quantitative and qualitative relationships within economic phenomena.
Omir Ainur, Adambekova Ainagul, Khishauyeva Zhanat, Zhanibekova Gaukhar, Amankeldi Nazigul   +4 more
doaj   +1 more source

Kliegl Bros. "pose slide" design artwork (Slides C5, C6, C7, and C8)

, 1890
Page [25] of original Kliegl Bros. "pose slide" design artwork on paper in binder, 1890s-early 1900s, undated. Page includes: C5 "Eve", C6 "Grecian Maid", C7 "Indian Brave", and C8 "Lady Moon"
Kliegl Bros. Universal Electric Stage Lighting Co.
core  

C5-(1-Propynyl)-2‘-deoxy-Pyrimidines Enhance Mismatch Penalties of DNA:RNA Duplex Formation^†

, 2016
UV melting experiments show that C5-(1-propynyl)ation of seven pyrimidines to give a fully propynylated oligodeoxynucleotide (PrODN) heptamer increases the thermodynamic stability of six Watson−Crick paired DNA:RNA duplexes by 8.2 kcal/mol, on average ...
Douglas H. Turner (27232), Thomas W. Barnes (2946153)   +1 more
core   +1 more source

Characterising the original anti-C5 function-blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5.

, 2020
The implication of complement in multiple diseases over the last twenty years has fuelled interest in developing anti-complement drugs. To date, the focus has been on C5; blocking cleavage of C5 prevents formation of two pro-inflammatory activities, C5a ...
Wioleta M Zelek (9469988), Andrea Brancale (220600), Bryan Paul Morgan (6437393), Brigitta Stockinger (277480), Georgina E Menzies (9469991)   +4 more
core  

Placental disposition of eculizumab, C5 and C5‐eculizumab in two pregnancies of a woman with paroxysmal nocturnal haemoglobinuria

, 2021
Contains fulltext : 232079.pdf (Publisher’s version ) (Open Access)Eculizumab is known to cross the placenta to a limited degree, but recently therapeutic drug levels in cord blood were found in a single case.
Petra H.H. van den Broek, Joris van Drongelen, Olivier W.H. van der Heijden, Broek, P.H.H. van den, Russel, F.G.M., Rick Greupink, Sarlea, A., Heijden, O.W.H. van der, Eliesen, G.A.M., Drongelen, J. van, Volokhina, E.B., Andrei Sarlea, Elena B. Volokhina, Frans G.M. Russel, Gaby A.M. Eliesen, Langemeijer, S.M., Saskia Langemeijer, Greupink, R.   +17 more
core   +1 more source

Supplemental Material: Enthalpy of Solvation Correlations for Gaseous Solutes Dissolved in Linear Alkanes (C5 thru C16) Based on the Abraham Model [PDF]

, 2007
This document includes supplemental material to an article titled "Enthalpy of solvation correlations for gaseous solutes dissolved in linear alkanes (C5 thru C16) based on the Abraham model," published in QSAR & Combinatorial ...
Abraham, M. H. (Michael H.), Mintz, Christina, Burton, Katherine, Acree, William E. (William Eugene)   +3 more
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Characterising a pH-switch anti-C5 antibody as a tool for human and mouse complement C5 purification and cross-species inhibition of classical and reactive lysis [PDF]

, 2018
C5 plays a major role in complement activation; C5 convertase cleaves C5 into the pro‐inflammatory C5a, and C5b, the nidus for the formation of the lytic membrane attack complex.
Zelek, Wioleta M., Harris, Claire L., Walters, David, Stott, Matthew, Morgan, B. Paul   +4 more
core   +1 more source

Theoretical study of the decomposition pathways and products of C5- perfluorinated ketone (C5 PFK)

, 2016
Due to the high global warming potential (GWP) and increasing environmental concerns, efforts on searching the alternative gases to SF6, which is predominantly used as insulating and interrupting medium in high-voltage equipment, have become a hot topic ...
Yanhui Lu, Yuwei Fu, Xi Li, Aijun Yang, Yi Wu, Mingzhe Rong, Xiaohua Wang, Guohui Han   +7 more
core   +1 more source