Results 41 to 50 of about 431,908 (196)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

CA-125 requisition pattern in a tertiary care hospital in central India and necessary modifications

Asian Journal of Medical Sciences, 2017
Background: Utility of CA-125 is not limited to being tumour marker for only epithelial ovarian carcinoma but it has also been found to be elevated in various other benign and malignant conditions.
Dnyanesh B Amle
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Role of CA125 in the Diagnosis of Acute Appendicitis

Eurasian Journal of Emergency Medicine, 2017
Aim: Acute appendicitis (AA) is the most common surgical emergency in the world, and its diagnosis is mainly dependent on clinical findings. Recently, secretion of CA125 from peritoneal cells due to inflammatory stimulus has been shown.
Barış Sevinç, Ersin Turan, Hüseyin Kurku, Ömer Karahan   +3 more
doaj   +1 more source

Predictive Value of Ca-125 in the Outcome of Cases of Threatened Abortion [PDF]

International Journal of Medical Arts
Background: Threatened abortion is one of the most common obstetric complications in the first trimester and poses a significant risk for pregnancy loss.
Mohamed Mahmoud, Rashed Mohamed Rashed, Alaa El Arshal   +2 more
doaj   +1 more source

Serum levels of carbohydrate antigen 125 in combination with N-terminal pro-brain natriuretic peptide in patients with acute decompensated heart failure [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Carbohydrate antigen 125 (CA-125) is an emerging prognostic biomarker for heart failure. We aimed to test the long-term prognostic value of CA-125 in combination with N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with ...
Jae Yong Yoon, Dong Heon Yang, Hyun Jun Cho, Nam Kyun Kim, Chang-Yeon Kim, Jihyun Son, Jae-Hyung Roh, Se Yong Jang, Myung Hwan Bae, Jang Hoon Lee, Hun Sik Park, Yongkeun Cho, Shung Chull Chae   +12 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Diagnostic Value of Serum Cancer Antigen 125, Carcinoembryonic Antigen, Cancer Antigen 19-9, Anti Müllerian Hormone, White Blood Cell Count, Platelet Count, and Neutrophil to Lymphocyte Ratio in Endometriosis: A Retrospective Study [PDF]

International Journal of Fertility and Sterility
Background: Endometriosis is among the leading causes of morbidity in the female population worldwide. Currently, the definite diagnosis of endometriosis depends on laparoscopy as the gold-standard method.
Behnaz Nouri, Niki Talebian, Ladan Kharaz, Mahdi Falah Tafti   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Ovarian fibroma: An unusual morphological presentation with elevated CA-125

Indian Journal of Pathology and Microbiology, 2008
This paper reports a case of a 42 year old female patient who presented with a large multi septate, predominantly cystic ovarian mass with elevated CA-125 levels. A diagnosis of malignant ovarian tumour was made on grounds of pre operative investigations
Arya Anupama, Rao Seema, Agarwal Shweta, Arora Rashmi, Gupta Kusum, Dhawan Indrani   +5 more
doaj