Results 61 to 70 of about 431,908 (196)

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali   +14 more
wiley   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

open access: yesArthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge   +6 more
wiley   +1 more source

Cancer Antigen 125 during Pregnancy in Women without Ovarian Tumor Is Not Often Rising

open access: yesObstetrics and Gynecology International, 2018
Objective. To determine the percentage of rising serum cancer antigen (CA-125) in singleton pregnant women whose ultrasonographical findings were normal. Methods.
Rattapon Amampai, Prapaporn Suprasert
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian   +4 more
wiley   +1 more source

More than 15 Years of CA 125: What is Known about the Antigen, Its Structure and Its Function

open access: yesThe International Journal of Biological Markers, 1998
In 1997 CA 125 celebrated its 15th anniversary. Since the discovery of OC 125, an antibody that recognizes CA 125, by Bob Bast and his colleagues, considerable progress has been made toward the development of more sensitive and more precise assay systems.
T.J. O'Brien   +3 more
doaj   +1 more source

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

open access: yesArthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang   +21 more
wiley   +1 more source

Comparison of Serum CA-125 Level in Ruptured and Unruptured Tubal Pregnancies in Yazd/Iran during 2001-2006 [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2009
Background & Aims: This study aimed to determine if serial measurement of serum CA-125 level could be used as a useful test in the differential diagnosis of intact and ruptured tubal pregnancies. Methods: In a single-blind prospective controlled clinical
L Sekhavat, M Mojibian, M Karimi zarchi
doaj  

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

open access: yesArthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee   +4 more
wiley   +1 more source

CCNE1 EXPRESSION AND CA-125 LEVELS IN HIGH GRADE SEROUS CARCINOMA OVARY AT MOHAMMAD HOESIN HOSPITAL PALEMBANG ; A SINGLE-INSTITUTION DESCRIPTIVE STUDY

open access: yesJurnal Kedokteran dan Kesehatan
High grade serous carcinoma (HGSC) of the ovary is the dominant subtype causing death from ovarian cancer. CCNE1 amplification occurs in 20% of ovarian HGSC and is associated with recurrence after platinum chemotherapy. Assessment of CCNE1 expression can
Dianli Fitriani   +2 more
doaj   +1 more source

The role of preoperative serum cancer antigen 125 in malignant ovarian germ cell tumors

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2018
Objective: To determine the role of preoperative serum cancer antigen 125 (CA 125) in malignant ovarian germ cell tumors (MOGCTs). Materials and methods: Using information from medical databases of Asan Medical Center (Seoul, Korea), we investigated 161 ...
Ju-Hyun Kim   +5 more
doaj   +1 more source

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