Results 231 to 240 of about 382,408 (297)

Acid ceramidase overactivity drives ceramide loss, leading to atopic dry skin and Th2‐skewed immune polarization

open access: yesThe Journal of Pathology, EarlyView.
Abstract Ceramide deficiency in the stratum corneum (SC) is a key etiological factor in atopic dermatitis (AD). To clarify the direct role of SC ceramide depletion in impairing SC barrier and water‐holding functions and in initiating AD‐like skin symptoms and disease‐specific molecular alterations, we generated Tg mice overexpressing a mutant form of ...
Mariko Takada   +8 more
wiley   +1 more source

A Rare Cause of Female Virilization: A Case Report. [PDF]

open access: yesCureus
Realista R   +3 more
europepmc   +1 more source

Genomic and Clinical Impact of Smoking on Therapeutic Outcomes in Prostate Cancer: A Public Databases Analysis

open access: yesThe Prostate, EarlyView.
ABSTRACT Background In prostate cancer (PCa), smoking history is associated with more aggressive clinicopathological features, reduced efficacy of androgen deprivation therapy, and poorer overall survival (OS). However, its impact on survival outcomes in patients receiving taxane chemotherapy, poly ADP‐ribose polymerase inhibitor (PARPi), or immune ...
Tomoya Hatayama   +16 more
wiley   +1 more source

Interfacial Chemistry‐Tailored Silica&Metal‐Based Heterostructures: from Rational Design to Antibacterial Applications

open access: yesSmall, EarlyView.
This review explores how interfacial engineering of silica&metal‐based nanohybrids enables precise architectural control, leveraging the structural and functional contributions of silica to overcome the inherent limitations of meta‐based materials. The antibacterial performance of these nanohybrids including membrane disruption, stimuli‐responsive ...
Dan Cheng, Yuchao Gu, Chengzhong Yu
wiley   +1 more source

Diagnostic accuracy of ultrasound models for assessment of ovarian tumors: systematic review and meta‐analysis

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Accurate preoperative classification of ovarian tumors is essential for guiding treatment. There is an increasing body of data evaluating ultrasound‐based models for this purpose in diverse clinical settings. The aim of this systematic review and meta‐analysis was to generate up‐to‐date evidence on the diagnostic accuracy of the most
E. Lems   +7 more
wiley   +1 more source

Recent advances of non‐invasive sensors for smart wearable respiratory monitoring

open access: yesVIEW, EarlyView.
Respiration contains rich physiological and pathological information, making it one of the most fundamental and continuous vital signs. Respiration monitoring is a non‐invasive and simple, but incredibly powerful, tool for assessing health, managing disease, and tracking fitness.
Jianhui Chen   +8 more
wiley   +1 more source

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