Small, EarlyView.ABSTRACT We introduce RNA‐DNA fusomers, a new class of chemically synthesized oligonucleotides that combine the versatile properties of RNA and DNA within a single sequence and self‐assemble into higher‐order functional structures via a simple one‐pot annealing reaction.
Yasmine Radwan +21 more
wiley +1 more source
Clinical and Molecular Signatures of Gallbladder Lesions: Insights into Metabolic and Inflammatory Pathways. [PDF]
Diagnostics (Basel)Bojan A +12 more
europepmc +1 more source
DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity
Small, EarlyView.DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley +1 more source
Elevated plasma cancer antigen-125 level is associated with increased risk of new-onset atrial fibrillation after acute myocardial infarction. [PDF]
Front Cardiovasc MedFu Y, Zuo K, Chen M, Xu L, Zhao L.
europepmc +1 more source
The Chemical Record, EarlyView.Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer +11 more
wiley +1 more source
Mucin Biology as a Local Diagnostic and Promising Therapeutic Target in Endometriosis: Expression and Glycosylation Profiling. [PDF]
Int J Mol SciVelho RV +8 more
europepmc +1 more source
Nonthermal plasma approaches for combating implant‐associated infections: A compendious review
VIEW, EarlyView.Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe +8 more
wiley +1 more source
Risks of pelvic inflammatory disease and bacterial vaginosis in adenomyosis patients using levonorgestrel intrauterine device or oral norethindrone. [PDF]
Front Endocrinol (Lausanne)Niu SY, Yi YC, Shih YH, Tseng JJ.
europepmc +1 more source
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
VIEW, EarlyView.This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source