Results 31 to 40 of about 2,529,224 (293)

Preoperative and Longitudinal Serum Levels of CA 125 and CA 15.3 in Patients with Breast Cancer

open access: yesThe International Journal of Biological Markers, 1989
Serum levels of ovarian carcinoma antigen (CA 125) and breast carcinoma antigen (CA 15.3) were determined in 237 patients with breast carcinoma, 121 before any therapy and 116 after initial treatment, during uneventful follow-up or at the time of relapse.
Y.T. Omar   +7 more
doaj   +1 more source

What do we know about the origin of CA 125?

open access: yes, 1993
The murine monoclonal antibody OC 125 recognizes an epitope on a molecule called Cancer Antigen 125 (CA 125). The CA 125 antigen is expressed in amnion and its derivatives of fetal coelomic epithelia (such as Müllerian epithelia, peritoneum, pleura and ...
Bischof P
core   +1 more source

Assessing prognosis in metastatic pancreatic cancer by the serum tumor marker CA 19-9: Pretreatment levels or kinetics during chemotherapy? [PDF]

open access: yes, 2007
Background: The carbohydrate antigen 19-9 (CA 19-9) is currently the most widely used serum tumor marker in pancreatic cancer (PC). CA 19-9 pretreatment levels as well as CA 19-9 kinetics during systemic chemotherapy can provide prognostic information ...
Holdenrieder, Stefan   +5 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Preoperative measurement of serum CA-125 levels: is it useful in the risk assessment of low volume lymph node disease in cervical cancer?

open access: yesRomanian Journal of Laboratory Medicine, 2017
BACKGROUND: Elevated serum cancer antigen 125 (CA-125) is observed in some cervical cancers (CCs). Is the correlation of CA-125 with the presence of nodal events useful in predicting early metastasis to the lymph nodes?
Sniadecki Marcin   +6 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

EVALUATION OF THE ASSOCIATION OF TUMOR BIOMARKERS WITH CHILDHOOD CANCERS

open access: yesHematology, Transfusion and Cell Therapy
Objective: We aimed to investigate the indications for Carbohydrate antigen 19-9 (CA 19-9), carbohydrate antigen 125 (CA-125), carbohydrate antigen 15-3 (CA15-3) and carcinoembryogenic antigen (CEA) tumor biomarkers, less commonly used in children, and ...
Şule ÇALIŞKAN KAMIŞ   +2 more
doaj   +1 more source

Evaluation of LDH, AFP, b-hCG and tumour markers CEA and CA-125 in sera of Iraqi patients with ovarian cancer [PDF]

open access: yesScripta Medica
Background/Aim: Ovarian cancer is still a big health concern, with few early detection options. The present research aimed to explore the test's usefulness of blood levels of cancer antigen 125 (CA-125), carcinoembryonic antigen (CEA), Alpha-fetoprotein (
Jassim Dawood Yasser   +3 more
doaj   +1 more source

Validation of a Multivariate Serum Profile for Epithelial Ovarian Cancer Using a Prospective Multi-Site Collection [PDF]

open access: yes, 2010
In previous studies we described the use of a retrospective collection of ovarian cancer and benign disease samples, in combination with a large set of multiplexed immunoassays and a multivariate pattern recognition algorithm, to develop an 11-biomarker ...
Brigitte E. Miller   +20 more
core  

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