Results 91 to 100 of about 1,191,068 (306)

Evaluation the Sensitivity and Specificity of CA 19-9 Test in Gastric Adenocarcinoma

open access: yesپزشکی بالینی ابن سینا, 2006
Introduction & Objective: The objective of this study was to determine the sensitivity and specificity of CA 19-9 test in diagnosis of gastric cancer patients.
Mohammad Jafari
doaj  

Different Tumour Marker Kinetics as Prognosticators in Patients with Adenocarcinoma of Gall Bladder Undergoing Chemotherapy: A Cohort Study [PDF]

open access: yesNational Journal of Laboratory Medicine
Introduction: Gallbladder Cancer (GBC) is the most common malignancy of the biliary tract worldwide. Patients do not have specific symptoms, and therefore, GBC is usually diagnosed at an advanced stage.
Pritilata saha   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. [PDF]

open access: yes, 1988
Autoantibodies to mitochondrial antigens are characteristic of the autoimmune liver disease primary biliary cirrhosis (PBC), but the precise antigenic determinants recognized by these antibodies have not been defined.
Ansari, A   +4 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Reference Limits for Chromogranin A, CYFRA 21-1, CA 125, CA 19-9 and Carcinoembryonic Antigen in Patients with Chronic Kidney Disease

open access: yesThe International Journal of Biological Markers, 2017
Background Patients with chronic kidney disease (CKD) may have increased plasma concentrations of some tumor markers even when no cancer is present.
Gustav Mikkelsen   +4 more
doaj   +1 more source

Elevated serum CA 19-9 levels in patients with pulmonary nontuberculous mycobacterial disease

open access: yesBrazilian Journal of Infectious Diseases, 2016
Increased serum CA 19-9 levels in patients with nonmalignant diseases have been investigated in previous reports. This study evaluates the clinical significance of serum CA 19-9 elevation in pulmonary nontuberculous mycobacterial disease and pulmonary ...
Ji Young Hong   +9 more
doaj   +1 more source

Genomic biomarkers in prostate cancer. [PDF]

open access: yes, 2018
Prostate cancer is the most common non-cutaneous cancer among men in the United States. In the last decade there has been a rapid expansion in the field of biomarker assays for diagnosis, prognosis, and treatment prediction in prostate cancer.
Cooperberg, Matthew R   +3 more
core  

Th17 responses are not altered by natural exposure to seasonal allergens in pollen-sensitive patients [PDF]

open access: yes, 2016
Background: Allergic rhinitis affects 10–30 % of the global population and this number is likely to increase in the forthcoming years. Moreover, it commonly co-exists with allergic asthma as a chronic allergic respiratory syndrome. While the involvement
Czesnikiewicz-Guzik, Marta   +10 more
core   +3 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

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