Results 91 to 100 of about 42,805 (221)

PARP inhibition: a promising therapeutic target in ovarian cancer [PDF]

, 2015
Ovarian cancer is burdened by the highest mortality rate among gynecological cancers. Gold standard is represented by the association of platinum-taxane -based chemotherapy and radical surgery.
Abdul Halim, T, BENEDETTI PANICI, PIERLUIGI, CASORELLI, ASSUNTA, DI DONATO, VIOLANTE, DOMENICI, LAVINIA, GASPARRI, MARIALUISA, IMPERIALE, LUDOVICA, MARCHETTI, CLAUDIA, MONTI, Marco, MUSELLA, ANGELA, MUZII, LUDOVICO, PALAIA, INNOCENZA, PECORINI, Francesco, RUSCITO, ILARY, SALERNO, LAURA   +14 more
core   +1 more source

Aquaporin‐1 differentiates intrahepatic cholangiocarcinoma from liver metastases of pancreatic ductal adenocarcinoma

Histopathology, EarlyView.
Differentiating intrahepatic CCA from PDAC metastatic to the liver is critical for the clinical management of patients with pancreatobiliary cancers. AQP1 has demonstrated an excellent discriminatory performance in this clinical scenario. Aims Differentiating intrahepatic cholangiocarcinoma (iCCA) from metastatic ductal adenocarcinoma of the pancreas ...
Leoncini Giuseppe, Barella Marco, Droz Dit Busset Michele, Gentili Marco, Bodini Beatrice, Ronchetti Simona, Cari Luigi, Mazzaferro Vincenzo   +7 more
wiley   +1 more source

Association between serum CA125 levels in preeclampsia and its severity among women in Lagos, South-West Nigeria

Hypertension in Pregnancy, 2018
Background: Preeclampsia is a syndrome of unknown etiology characterized by hypertension, proteinuria, and/or organ dysfunction. CA125 is an antigenic determinant recognized by the murine monoclonal antibody OC125 quantified by radioimmunoassay. Its role
Gbemisola E. Osanyin, Kehinde S. Okunade, Ayodeji Ayotunde Oluwole   +2 more
doaj   +1 more source

Amniotic fluid embolism pathophysiology suggests the new diagnostic armamentarium: β-tryptase and complement fractions C3-C4 are the indispensable working tools [PDF]

, 2015
Amniotic fluid embolism (AFE) is an uncommon obstetric condition involving pregnant women during labor or in the initial stages after delivery. Its incidence is estimated to be around 5.5 cases per 100,000 deliveries.
Busardo', FRANCESCO PAOLO, Fineschi, Vittorio, Frati, Paola, Zaami, Simona   +3 more
core   +2 more sources

Elevated CA125 levels in association with endometriosis

Journal of Obstetrics and Gynaecology, 2000
(2000). Elevated CA125 levels in association with endometriosis. Journal of Obstetrics and Gynaecology: Vol. 20, No. 2, pp. 207-207.
J, Bhaumik, N C, Hill
openaire   +2 more sources

Doppel as an early‐stage biomarker promoting EMT and dissemination in ovarian cancers

International Journal of Cancer, Volume 158, Issue 6, Page 1755-1768, 15 March 2026.
What's new? Existing biomarkers for ovarian cancer (OC) lack the sensitivity and specificity needed to consistently distinguish the malignancy from non‐ovarian influences and other cancers. Here, the authors explored the ability of the prion‐like protein Doppel, normally found in the male testes, to detect OC.
Zulfikar Azam, Xiaojun Zhang, Riajul Wahab, Md Mahedi Hasan, Shivaniben Dhadhal, Bowon Kang, Md Mynul Hassan, Mazharul Karim, Jeong Uk Choi, Muhit Rana, Jian‐Ying Zhang, Sourav Roy, Youngro Byun, In‐San Kim, Jae Yun Song, Eugene P. Toy, Sireesha Y. Reddy, Farzana Alam, Taslim A. Al‐Hilal   +18 more
wiley   +1 more source

Detecting FR‐⍺ Expression Level in Cytology Effusion Specimens From Ovarian Cancer and Comparing It With Tissue Specimens

Diagnostic Cytopathology, Volume 54, Issue 3, Page 197-205, March 2026.
ABSTRACT Background Folate receptor‐⍺ (FR‐⍺) is an attractive target for targeted therapy. Mirvetuximab soravtansine (MIRV) has been approved by the United States Food and Drug Administration (FDA) for treating adult patients with FR‐⍺ positive, platinum‐resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Therefore,
Yadan Ma, Xiaofei Yu, Xiaohong Duan, Siqian Huang, Sishi Bai, Baizhou Li   +5 more
wiley   +1 more source

A Cost Consequence Analysis of Seven Diagnostic Strategies for Ovarian Cancer: A Model‐Based Economic Evaluation

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 680-689, March 2026.
ABSTRACT Objective To assess the costs and consequences of seven diagnostic strategies for ovarian cancer in pre‐ and post‐menopausal women with symptoms in secondary care. Design Economic evaluation alongside a prospective single‐arm diagnostic accuracy study.
Samuel J. Perry, Donal Griffin, Eleanor V. Williams, Tracy E. Roberts, Fong Lien Kwong, Sarah Williams, Jon Deeks, Katie Scandrett, Ridhi Agarwal, Sudha S. Sundar, Mark Monahan   +10 more
wiley   +1 more source

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Prognostic Value of CA125 Kinetics and Half-Life in Advanced Ovarian Cancer

The International Journal of Biological Markers, 2000
This retrospective study was undertaken in order to assess the prognostic value of prechemotherapy serum CA125 level, CA125 kinetics, and CA125 half-life compared to the ten common clinicopathological variables in patients with advanced ovarian cancer ...
S. Čolaković, V. Lukiç, L. Mitroviç, S. Jeliç MD, PhD, S. Susnjar, J. Marinkoviç   +5 more
doaj   +1 more source