Results 81 to 90 of about 37,370 (230)

Machine Learning‐Derived Immune Gene Signature Predicts Prognosis and Therapeutic Vulnerabilities in Multiple Myeloma

open access: yesCancer Science, EarlyView.
An immune‐related 12‐gene signature developed through integrative machine learning stratified overall survival across multiple myeloma cohorts and remained independently associated with outcome. Single‐cell, somatic mutation, and transcriptome‐based drug‐response analyses further linked the signature to multicellular bone marrow context, distinct ...
Kai Wang   +10 more
wiley   +1 more source

CA125 Expression on Spontaneous Ovarian Adenocarinornas from Geriatric Laying Hens

open access: yes, 2007
Despite years of research ovarian cancer remains the most lethal of all gynecological malignancies. Ovarian cancer is the fourth leading cause of cancer death among women in the United States.
Jackson, Emily Dawn
core  

Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment

open access: yesThe FEBS Journal, EarlyView.
Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro   +13 more
wiley   +1 more source

Association between serum CA125 levels in preeclampsia and its severity among women in Lagos, South-West Nigeria

open access: yesHypertension in Pregnancy, 2018
Background: Preeclampsia is a syndrome of unknown etiology characterized by hypertension, proteinuria, and/or organ dysfunction. CA125 is an antigenic determinant recognized by the murine monoclonal antibody OC125 quantified by radioimmunoassay. Its role
Gbemisola E. Osanyin   +2 more
doaj   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad   +6 more
wiley   +1 more source

Paraurethral Endometrioid Carcinoma Arising From Ectopic Endometriosis: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Malignant transformation of endometriosis is rare and most commonly involves the ovary; transformation from paraurethral endometriosis is exceedingly rare. Case Presentation A 73‐year‐old postmenopausal woman with prior ovarian endometrioma presented with dysuria and voiding difficulty.
Keita Ogasawara   +9 more
wiley   +1 more source

Is tissue CA125 expression in epithelial ovarian adenocarcinoma heterogenic?

open access: yes, 2013
To evaluate if heterogeneity of tissue cancer antigen 125 (CA125) expression is present in epithelial serous adenocarcinomas. Furthermore, to investigate whether there is a correlation between levels of CA125 tissue expression, serum level of CA125 ...
Høgdall, Claus K   +5 more
core   +1 more source

Leiomyosarcoma of the Renal Vein That Enlarged Laterally While Preserving the Structure of the Renal Vein Lumen

open access: yesIJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Primary renal vein leiomyosarcoma is an extremely rare disease and the tumor often infiltrates the vessel wall. We report a case of primary renal vein leiomyosarcoma that enlarged while preserving the structure of the renal vein lumen.
Naoki Tashiro   +9 more
wiley   +1 more source

Przydatność oceny stężenia markera CA125 w diagnostyce guzów jajnika ze szczególnym uwzglêdnieniem torbieli endometrialnych

open access: yes, 2010
Background: CA125 is a mucin-derived glycoprotein. It occurs and is marked mostly among the patients withan ovarian tumour. Nowadays, CA125 antigen is considered to be the best biochemical marker for non-mucinousovarian cancers.
Katarzyna Wójcik-Krowiranda   +2 more
core  

Multi‐Omics Profiling of High‐Grade Serous Ovarian Cancer Reveals an Inflammation‐Related Lipid Metabolism Subtype Associated With Platinum Resistance

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao   +11 more
wiley   +1 more source

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