Results 81 to 90 of about 37,370 (230)
An immune‐related 12‐gene signature developed through integrative machine learning stratified overall survival across multiple myeloma cohorts and remained independently associated with outcome. Single‐cell, somatic mutation, and transcriptome‐based drug‐response analyses further linked the signature to multicellular bone marrow context, distinct ...
Kai Wang +10 more
wiley +1 more source
CA125 Expression on Spontaneous Ovarian Adenocarinornas from Geriatric Laying Hens
Despite years of research ovarian cancer remains the most lethal of all gynecological malignancies. Ovarian cancer is the fourth leading cause of cancer death among women in the United States.
Jackson, Emily Dawn
core
Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment
Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro +13 more
wiley +1 more source
Background: Preeclampsia is a syndrome of unknown etiology characterized by hypertension, proteinuria, and/or organ dysfunction. CA125 is an antigenic determinant recognized by the murine monoclonal antibody OC125 quantified by radioimmunoassay. Its role
Gbemisola E. Osanyin +2 more
doaj +1 more source
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad +6 more
wiley +1 more source
Paraurethral Endometrioid Carcinoma Arising From Ectopic Endometriosis: A Case Report
ABSTRACT Introduction Malignant transformation of endometriosis is rare and most commonly involves the ovary; transformation from paraurethral endometriosis is exceedingly rare. Case Presentation A 73‐year‐old postmenopausal woman with prior ovarian endometrioma presented with dysuria and voiding difficulty.
Keita Ogasawara +9 more
wiley +1 more source
Is tissue CA125 expression in epithelial ovarian adenocarcinoma heterogenic?
To evaluate if heterogeneity of tissue cancer antigen 125 (CA125) expression is present in epithelial serous adenocarcinomas. Furthermore, to investigate whether there is a correlation between levels of CA125 tissue expression, serum level of CA125 ...
Høgdall, Claus K +5 more
core +1 more source
ABSTRACT Introduction Primary renal vein leiomyosarcoma is an extremely rare disease and the tumor often infiltrates the vessel wall. We report a case of primary renal vein leiomyosarcoma that enlarged while preserving the structure of the renal vein lumen.
Naoki Tashiro +9 more
wiley +1 more source
Background: CA125 is a mucin-derived glycoprotein. It occurs and is marked mostly among the patients withan ovarian tumour. Nowadays, CA125 antigen is considered to be the best biochemical marker for non-mucinousovarian cancers.
Katarzyna Wójcik-Krowiranda +2 more
core
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao +11 more
wiley +1 more source

