Results 91 to 100 of about 43,558 (239)

Specific antitumor activity of anti-CA125 CAR-T lymphocytes against CA125-positive and CA125-negative cells

Sechenov Medical Journal
Aim. To evaluate the antitumor efficacy of our developed drug based on cytotoxic T lymphocytes genetically modified with a chimeric antigen receptor (CAR) specific to the CA125 antigen in relation to both CA125-positive and CA125negative cell cultures.Materials and methods.
T. M. Kulinich, Ya. Yu. Kiseleva, A. M. Shishkin, E. A. Kudinova, O. B. Knyazeva, R. Ranjit, V. K. Bozhenko, V. A. Solodky   +7 more
openaire   +2 more sources

Elevated CA125 levels in association with endometriosis

Journal of Obstetrics and Gynaecology, 2000
(2000). Elevated CA125 levels in association with endometriosis. Journal of Obstetrics and Gynaecology: Vol. 20, No. 2, pp. 207-207.
J, Bhaumik, N C, Hill
openaire   +2 more sources

Enhancing Community‐Based Nursing Decision Support: Machine Learning Models for Diabetes Risk Prediction Using Home Health Nursing Notes

Public Health Nursing, EarlyView.
ABSTRACT Objectives This study aimed to identify high‐risk factors for type 2 diabetes and develop a machine learning (ML)–based diabetes prediction model using nursing notes from home health care. Design Retrospective cohort study. Sample A total 7896 medical records from 1747 patients aged ≥ 20 years who received home health care at a university ...
Doyeon LIM, Aeri KIM, Hana LEE, Kyungmi WOO   +3 more
wiley   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Polymorphisms of MUC16 (CA125) and MUC1 (CA15.3) in Relation to Ovarian Cancer Risk and Survival [PDF]

, 2014
Objective: To examine single nucleotide polymorphism (SNPs) in MUC16 (CA125) and MUC1 (CA15.3) in relation to ovarian cancer risk and survival. Methods: We genotyped germline variants of MUC16 (rs2547065, rs1559168, rs12984471, rs2121133) and MUC1 ...
Cramer, Daniel W., Terry, Kathryn L., Titus, Linda J., Tworoger, Shelley S., Vitonis, Allison F., Williams, Kristina A.   +5 more
core   +1 more source

HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma

International Journal of Cancer, Volume 158, Issue 11, Page 2957-2971, 1 June 2026.
What's new? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang, Ken Yamaguchi, Kohei Hamada, Yuko Hosoe, Yuka Mise, Sachiko Kitamura, Zhihong Liu, Hairong Wei, Zhenhai Gao, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Rin Mizuno, Taito Miyamoto, Junzo Hamanishi, Masaki Mandai   +15 more
wiley   +1 more source

Prognostic Value of CA125 Kinetics and Half-Life in Advanced Ovarian Cancer

The International Journal of Biological Markers, 2000
This retrospective study was undertaken in order to assess the prognostic value of prechemotherapy serum CA125 level, CA125 kinetics, and CA125 half-life compared to the ten common clinicopathological variables in patients with advanced ovarian cancer ...
S. Čolaković, V. Lukiç, L. Mitroviç, S. Jeliç MD, PhD, S. Susnjar, J. Marinkoviç   +5 more
doaj   +1 more source

Diagnostic Value of the Neutrophil/Lymphocyte Ratio, Platelet/Lymphocyte Ratio, and Thrombocytosis in the Preoperative Investigation of Ovarian Masses [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective To evaluate the diagnostic accuracy of cancer antigen 125 (CA125) and complete blood count (CBC) parameters, such as the neutrophil to lymphocyte ratio (NLR), the platelet to lymphocyte ratio (PLR), and thrombocytosis in patients with ovarian ...
Adriana Yoshida, Luís Otavio Sarian, Marcos Marangoni Junior, Isis Caroline Firmano, Sophie Françoise Derchain   +4 more
doaj   +2 more sources

Prognostic value of CA125 in advanced heart failure patients [PDF]

, 2009
INTRODUCTION: Serum levels of CA125 are often high in advanced heart failure (AHF) patients. AIM: To determine the predictive value of CA125 in forecasting the occurrence of death or cardiac transplantation in an AHF population.
Coelho, L, Costa, S, Franco, F, Monteiro, P, Monteiro, S, Oliveira, L, Providência, LA, Vieira, H   +7 more
core  

The cost-effectiveness of screening for ovarian cancer: results from the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) [PDF]

, 2017
Background: To assess the within trial cost-effectiveness of an NHS ovarian cancer screening (OCS) programme using data from UKCTOCS and extrapolate results based on average life expectancy. Methods: Within trial economic evaluation of no screening (C)
Aleksandra Gentry-Maharaj, Alistair J McGuire, Andy Ryan, David Oram, Derek Cruickshank, DY Lin, EC Fieller, G Sfakianos, I Jacobs, Ian J Jacobs, Ian Scott, J Barrett, Jatinderpal K Kalsi, John Murdoch, Jonathan Herod, Karin Williamson, Keith Godfrey, Lesley Fallowfield, Mahesh Parmar, Maria Raikou, Matthew Burnell, Mourad W Seif, Naveena Singh, Nazar N Amso, P Royston, R Etzioni, Robert Woolas, S Edwards, Simon Leeson, Stephen Dobbs, Steven J Skates, Stuart Campbell, Susan K Davies, Tim Mould, Usha Menon   +34 more
core   +2 more sources