Results 81 to 90 of about 42,942 (233)

CA125: Holy Grail or a Poisoned Chalice [PDF]

Nephron Clinical Practice, 2005
The history of (and perhaps the lessons to be learned from) peritoneal CA125 investigation presents no better example of the diffi culties in assigning the status of a ‘marker’ predictive of membrane dysfunction to factors measured in dialysis effl uent. In 1995, Visser et al. [3] were the fi rst to suggest that CA125 could be used as ‘a bulk marker of
Nicholas, Topley, Daryn, Michael, Timothy, Bowen   +2 more
openaire   +2 more sources

Three‐dimensional patient‐derived endometriosis model for drug evaluation

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this study, we developed a coculturing model with stromal cells and epithelial organoids to mimic the endometriotic lesion and for further evaluation of drug effects. Abstract Introduction Endometriomsis (EMs) is a complex and chronic gynecological disease characterized by distressing symptoms.
Yuqi Li, Wei Shao, Xiaoxiao Gao, Yongxing Wang, Jinzhi Li, Liansuo Zhang, Yanyan Xing, Wentao Su, Yan Cheng, Li Wang, Songping Liu   +10 more
wiley   +1 more source

Regional perturbation of gene transcription is associated with intrachromosomal rearrangements and gene fusion transcripts in high grade ovarian cancer. [PDF]

, 2019
Genomic rearrangements are a hallmark of cancer biology and progression, allowing cells to rapidly transform through alterations in regulatory structures, changes in expression patterns, reprogramming of signaling pathways, and creation of novel ...
Beck, Tim, E Francis, Kyle, Krzyzanowski, Paul, La Rose, Jose, McPherson, John, Normand, Josee, Rottapel, Robert, Sircoulomb, Fabrice, Stein, Lincoln, Suarez, Fernando, Yousif, Fouad   +10 more
core   +2 more sources

Analysis of Peripheral T Cell Profiling and Plasma Proteomics in Advanced NSCLC Patients Treated With Atezolizumab

Cancer Science, EarlyView.
This study found immune markers that may predict how well patients with advanced lung cancer respond to atezolizumab. Higher levels of certain T cells were linked to better survival. Specific patterns suggested a worse prognosis for some patients. ABSTRACT We investigated immunologic biomarkers that predict outcomes of patients with previously treated ...
Atsuto Mouri, Hiroshi Kagamu, Koji Tamada, Makoto Nishio, Hiroaki Akamatsu, Yasushi Goto, Hidetoshi Hayashi, Satoru Miura, Akihiko Gemma, Ichiro Yoshino, Toshihiro Misumi, Ryota Saito, Noriko Yanagitani, Fujita Masaki, Hiroshi Nokihara, Kazumi Nishino, Masahiro Seike, Tetsunari Hase, Osamu Hataji, Hiroaki Takeoka, Yosuke Kawashima, Hirotaka Kuroki, Masamichi Sugimoto, Hiroshi Kuriki, Tetsuya Mitsudomi   +24 more
wiley   +1 more source

Akurasi Kadar Lysophosphatidic Acid Plasma dan Ca125 Serum Penderita Tumor Ovarium Jenis Epitel untuk Prediktor Keganasan Ovarium

Indonesian Journal of Cancer, 2014
This study was conducted to determine and compare the sensitivity, specificity, positive predictive value and negative predictive value between CA125, Lysophosphatidic Acid Plasma (LPA) and combination of LPA - CA125 in patients with ovarian mass ...
TRI APRILIAWAN, BRAHMANA ASKANDAR
doaj   +1 more source

Comment on “GLM7 – A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity”

Advanced Science, EarlyView.
Peikai Sun, Zhipeng Fan, Lei Li
wiley   +1 more source

Systematic Multiplatform Discovery of Methylation Markers Enables Non‐Invasive Early Detection of Endometrial Cancer

Cancer Science, EarlyView.
We identified key endometrial cancer DNA methylation biomarkers (ZNF626, GRIA4, SPDYA) from cervical cells. The model achieved high endometrial cancer sensitivity and detected 92.86% of Stage I endometrial cancers using TCT samples. ABSTRACT Endometrial cancer, the most common gynecological malignancy with an annual increase of 1%–3%, lacks suitable ...
Yan Cai, Shuchao Chen, Zhen Wu, Jinxia Guan, Jie Zhao, Jianwei Ye, Baochen Du, Xiaoliang Han, Tong Shu, Guangpeng Zhou, Hong Zheng   +10 more
wiley   +1 more source

Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature

International Journal of Women's Health, 2022
Shaoyu Wang, Xinqin He, Huijuan Yang, Lihong Chen Department of Obstetrics and Gynecology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, People’s Republic of ChinaCorrespondence: Lihong Chen, Department of Obstetrics and ...
Wang S, He X, Yang H, Chen L
doaj  

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors [PDF]

, 2006
Background The mucin MUC16 and the glycosylphosphatidylinositol anchored glycoprotein mesothelin likely facilitate the peritoneal metastasis of ovarian tumors.
Sathyanarayana Bangalore K, Connor Joseph, Bera Tapan K, Ho Mitchell, Migneault Martine, Rancourt Claudine, Onda Masanori, Belisle Jennifer, Gubbels Jennifer AA, Lee Byungkook, Pastan Ira, Patankar Manish S   +11 more
core   +1 more source

Cervical Small Cell Neuroendocrine Carcinoma Initially Detected on Cytology: Diagnostic Pitfalls and Clues

Cytopathology, EarlyView.
This case describes the initial detection of cervical small cell neuroendocrine carcinoma on conventional endometrial and cervicovaginal liquid‐based cytology. Given its rarity and high aggressiveness, early recognition and rapid, intensive treatment are crucial for improving patient outcomes.
Yesul Jeong
wiley   +1 more source