Results 71 to 80 of about 2,901,202 (236)
Applied Medical InformaticsCancer Antigen 15-3 (CA 15-3) is a glycoprotein commonly linked to breast cancer. Monitoring CA 15-3 levels is crucial for tracking disease progression and evaluating treatment response in patients with metastatic breast cancer. Although fluctuations in
Alexandros CLOUVAS
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Comparison of the performance of three cancer antigen (CA) 15-3 immunoassays
Journal of Health Sciences, 2016 Introduction: In the present study we investigated the performance, precision, and recovery of three different automated methods in determining cancer antigen (CA) 15-3 levels. Methods: Serum samples were obtained from 60 hospitalized female patients. As
Nafija Serdarevic +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Applied Medical InformaticsCancer Antigen 15-3 (CA 15-3) is a glycoprotein often linked to breast cancer. Elevated levels of CA 15-3, above the normal reference range of 30 U/mL (units per milliliter), are frequently found in the blood of patients with metastatic breast cancer ...
Alexandros CLOUVAS
doaj
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Serum CA 549, CA 19-9, CA 15-3, and CEA Levels in Patients With Breast Cancer
Eurasian Journal of Medicine, 2019 -
Mahmut C. Başoğlu +7 more
doaj
CA 15-3, CRP, and LDH correlates with prognostic parameters in canine mammary neoplasms. [PDF]
Anim Reprod, 2023 Pinheiro BQ +5 more
europepmc +1 more source