Results 81 to 90 of about 97,542,255 (296)

Effect of Aflatoxin B1 in both Caco-2 and Caco-2/HT29-MTX models

, 2022
About effect of Aflatoxin B1 in both Caco-2 and Caco-2/HT29-MTX models within the scope of the intestinal absorption assessment and enabling formulations.FCT/MCTES for funding with national funds related to theearlyMYCO project (PTDC/MED-TOX/28762/2017 ...
Jordan, P., Vidal, N., Serrenho, I., Pereira, J., Matos, P., Alvito, P., Louro, H., Rolo, D.   +7 more
core  

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

Advanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu, Siyu Wang, Tong Lin, Jingyi Zhang, Jingya Yang, Dixiang Kang, Wenting Zhao, Na Yu, Meimei Wang   +8 more
wiley   +1 more source

Investigating the effect of resveratrol on apoptosis and regulation of gene expression of Caco-2 cells: Unravelling potential implications for colorectal cancer treatment

Open Chemistry
Colorectal cancer is known for its substantial impact on global morbidity and mortality, with higher prevalence in developed regions. This study delves into the potential treatment advantages of resveratrol (RSV) in addressing colorectal cancer ...
Al-Zharani Mohammed, Alkahtane Abdullah A., AL-Johani Norah S., Almutairi Bader, Alkeraishan Nora, Alarifi Saud, Alrajeh Sahirah M., Yaseen Khadijah N., Aljarba Nada H., Nasr Fahd A., Alkahtani Saad   +10 more
doaj   +1 more source

Two‐Dimensional Carrier Gas at Diamond and Cubic Boron Nitride (111) Interface: Role of Interfacial Bonding and Defects

Advanced Electronic Materials, EarlyView.
The study identifies four bonding configurations at the (111) diamond/c‐BN interface, where B or N atoms bond with either one or three carbon atoms. C‐B bonds create two‐dimensional (2D) hole gases, while C–N bonds create electron gases. Three‐C‐bonded interfaces show three times higher carrier density than one‐C‐bonded interfaces.
Shikha Saini, Konstantin Klyukin, Mengren Bill Liu, Mark J. Polking, Bilge Yildiz   +4 more
wiley   +1 more source

Investigation of the effects of Protocatechuic acid on apoptosis, oxidant and antioxidant status in Caco-2 colorectal cancer cells

Acta Medica Alanya
Aim: Protocatechuic acid (PCA) is one of the common phenolic acids found in many foods and plants and it has multiple biological activities. Although PCA has been investigated for its antioxidant, anti-inflammatory, and anticancer effects in various cell
Fatma Yıldız
doaj   +1 more source

Retinoic Acid Facilitates Toll-Like Receptor 4 Expression to Improve Intestinal Barrier Function through Retinoic Acid Receptor Beta

Cellular Physiology and Biochemistry, 2017
Background/Aims: Vitamin A (VA) protects the intestinal epithelial barrier by improving cell migration and proliferation. Our previous studies demonstrated that VA deficiency (VAD) during pregnancy suppresses the systemic and mucosal immune responses in ...
Yingying Li, Yuan Gao, Ting Cui, Ting Yang, Lan Liu, Tingyu Li, Jie Chen   +6 more
doaj   +1 more source

The transition from proliferation to differentiation in colorectal cancer is regulated by the calcium activated chloride channel A1. [PDF]

PLoS ONE, 2013
Breaking the balance between proliferation and differentiation in animal cells can lead to cancer, but the mechanisms maintaining this balance remain largely undefined.
Bo Yang, Lin Cao, Bin Liu, Colin D McCaig, Jin Pu   +4 more
doaj   +1 more source

Sinomenine decreased PGE₂ released from MDR-Caco-2 cells.

, 2014
MDR-Caco-2 and Caco-2 cells were cultured for 48 h in the presence or absence of 500 µM sinomenine, as indicated, and harvested. Supernatants were then collected for PGE2 measurement. Data are presented as mean ± SE.
Zhi-Jun Duan (573304), Ke-Hang Dai (573308), Zhen Liu (74646), Yu-Ling Li (573307), Guang-quan Mo (573310), Jiu-Yang Chang (573305), Rui Chu (573306), Zhi-feng Zhang (5659204), Qing-Yong Chang (573312)   +8 more
core   +1 more source

Stable Caco-2 Cell Line Construction

Bio-Protocol, 2012
This protocol describes the construction of Caco-2 stable cell lines using the Lipofectamine transfection method.
Lin Fang
doaj   +1 more source

Differentiation of CaCo-2 cells.

, 2013
A: Trans-epithelial electric resistance (TEER) was measured on CaCo-2 cells on filters during their differentiation. Measurements were performed before change of medium. TEER (Ω x cm2) was plotted against time. One representative experiment is shown with
Knut G. Berdal (281269), Bjørn Spilsberg (281266), Christer R. Wiik-Nielsen (281267), Arne Holst-Jensen (281268), Lene E. Johannessen (281265), Anja B. Kristoffersen (248227)   +5 more
core   +1 more source